Table 3

Effect of chronic GVHD on overall survival, disease-associated mortality, and treatment-related mortality after allogeneic hematopoietic cell transplantation for adult T-cell leukemia

OutcomeUnivariate analysis
Multivariate analysis
HR (95% CI)PHR (95% CI)P
Overall survival*     
    Limited chronic GVHD vs no chronic GVHD 0.71 (0.34-1.47) .353 0.72 (0.35-1.50) .385 
    Extensive chronic GVHD vs no chronic GVHD 1.45 (0.90-2.35) .131 1.40 (0.86-2.30) .176 
Disease-associated mortality†     
    Limited chronic GVHD vs no chronic GVHD 0.45 (0.14-1.46) .183 0.45 (0.14-1.44) .178 
    Extensive chronic GVHD vs no chronic GVHD 0.81 (0.39-1.67) .563 0.80 (0.39-1.64) .536 
Treatment-related mortality‡     
    Limited chronic GVHD vs no chronic GVHD 1.59 (0.64-3.95) .316 1.56 (0.63-3.87) .342 
    Extensive chronic GVHD vs no chronic GVHD 2.85 (1.41-5.77) .004 2.75 (1.34-5.63) .006 
OutcomeUnivariate analysis
Multivariate analysis
HR (95% CI)PHR (95% CI)P
Overall survival*     
    Limited chronic GVHD vs no chronic GVHD 0.71 (0.34-1.47) .353 0.72 (0.35-1.50) .385 
    Extensive chronic GVHD vs no chronic GVHD 1.45 (0.90-2.35) .131 1.40 (0.86-2.30) .176 
Disease-associated mortality†     
    Limited chronic GVHD vs no chronic GVHD 0.45 (0.14-1.46) .183 0.45 (0.14-1.44) .178 
    Extensive chronic GVHD vs no chronic GVHD 0.81 (0.39-1.67) .563 0.80 (0.39-1.64) .536 
Treatment-related mortality‡     
    Limited chronic GVHD vs no chronic GVHD 1.59 (0.64-3.95) .316 1.56 (0.63-3.87) .342 
    Extensive chronic GVHD vs no chronic GVHD 2.85 (1.41-5.77) .004 2.75 (1.34-5.63) .006 
*

There was no significant variable.

†

There was no significant variable.

‡

There was no other significant variable.

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