Relationship between histology and fecal biomarkers in patients with GI-GVHD
| Histology . | N . | Calprotectin . | Elastase . | α1-antitrypsin . |
|---|---|---|---|---|
| Apoptosis | ||||
| Absent | 8 | 408 (322-597) | 66 (28-188) | 10.6 (5.3-14.6) |
| Present | 24 | 37 (15-101) | 332 (144-450) | 2.1 (0.9-8.9) |
| P | .002 | .029 | .037 | |
| Infiltrate | ||||
| Absent | 2 | 5; 828 | 30; 84 | 0; 15.8 |
| Present | 29 | 61 (30-170) | 279 (142-439) | 3.9 (1.2-9.0) |
| P | ||||
| Vascular damage | ||||
| Absent | 28 | 54 (22-196) | 266 (138-441) | 3.5 (1.1-9.1) |
| Present | 4 | 276 (163-936) | 33 (15-106) | 11.2 (6.1-17.0) |
| P | .063 | .046 | .19 | |
| Epithelial abrasion | ||||
| Absent | 21 | 37 (18-141) | 279 (124-446) | 1.7 (0.9-8.8) |
| Present | 11 | 302 (83-472) | 157 (38-370) | 7.7 (3.9-14.7) |
| P | .017 | .22 | .074 |
| Histology . | N . | Calprotectin . | Elastase . | α1-antitrypsin . |
|---|---|---|---|---|
| Apoptosis | ||||
| Absent | 8 | 408 (322-597) | 66 (28-188) | 10.6 (5.3-14.6) |
| Present | 24 | 37 (15-101) | 332 (144-450) | 2.1 (0.9-8.9) |
| P | .002 | .029 | .037 | |
| Infiltrate | ||||
| Absent | 2 | 5; 828 | 30; 84 | 0; 15.8 |
| Present | 29 | 61 (30-170) | 279 (142-439) | 3.9 (1.2-9.0) |
| P | ||||
| Vascular damage | ||||
| Absent | 28 | 54 (22-196) | 266 (138-441) | 3.5 (1.1-9.1) |
| Present | 4 | 276 (163-936) | 33 (15-106) | 11.2 (6.1-17.0) |
| P | .063 | .046 | .19 | |
| Epithelial abrasion | ||||
| Absent | 21 | 37 (18-141) | 279 (124-446) | 1.7 (0.9-8.8) |
| Present | 11 | 302 (83-472) | 157 (38-370) | 7.7 (3.9-14.7) |
| P | .017 | .22 | .074 |
GI indicates gastrointestinal.