Rates of SR and cumulative incidence of CR by the initial stage of GI GVHD
| Marker . | Stage 1 . | Stage 2 . | Stage 3 . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N . | CR, % . | SR, % . | N . | CR, % . | SR, % . | N . | CR, % . | SR, % . | |
| All patients | 23 | 87 | 30 | 14 | 79 | 57 | 14 | 57 | 86 | 
| Calprotectin, μg/g stool | |||||||||
| < 100 | 20 | 85 | 25 | 8 | 88 | 25 | 7 | 86 | 71 | 
| ≥ 100 | 3 | 100 | 67 | 6 | 67 | 100 | 7 | 29 | 100 | 
| P | .25 | .21 | .27 | .021 | .022 | .46 | |||
| α1-AT, mg/g dw | |||||||||
| < 1.5 | 15 | 87 | 27 | 4 | 100 | 0 | 2 | 100 | 50 | 
| ≥ 1.5 | 8 | 88 | 38 | 10 | 70 | 80 | 12 | 50 | 92 | 
| P | .25 | .66 | .001 | .015 | .23 | .27 | |||
| No. of positive markers | |||||||||
| 0 | 14 | 86 | 21 | 4 | 100 | 0 | 2 | 100 | 50 | 
| 1 | 7 | 86 | 43 | 4 | 75 | 50 | 5 | 80 | 80 | 
| 2 | 2 | 100 | 50 | 6 | 67 | 100 | 7 | 29 | 100 | 
| P | .49 | .40 | .005 | .004 | .068 | .23 | |||
| Marker . | Stage 1 . | Stage 2 . | Stage 3 . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N . | CR, % . | SR, % . | N . | CR, % . | SR, % . | N . | CR, % . | SR, % . | |
| All patients | 23 | 87 | 30 | 14 | 79 | 57 | 14 | 57 | 86 | 
| Calprotectin, μg/g stool | |||||||||
| < 100 | 20 | 85 | 25 | 8 | 88 | 25 | 7 | 86 | 71 | 
| ≥ 100 | 3 | 100 | 67 | 6 | 67 | 100 | 7 | 29 | 100 | 
| P | .25 | .21 | .27 | .021 | .022 | .46 | |||
| α1-AT, mg/g dw | |||||||||
| < 1.5 | 15 | 87 | 27 | 4 | 100 | 0 | 2 | 100 | 50 | 
| ≥ 1.5 | 8 | 88 | 38 | 10 | 70 | 80 | 12 | 50 | 92 | 
| P | .25 | .66 | .001 | .015 | .23 | .27 | |||
| No. of positive markers | |||||||||
| 0 | 14 | 86 | 21 | 4 | 100 | 0 | 2 | 100 | 50 | 
| 1 | 7 | 86 | 43 | 4 | 75 | 50 | 5 | 80 | 80 | 
| 2 | 2 | 100 | 50 | 6 | 67 | 100 | 7 | 29 | 100 | 
| P | .49 | .40 | .005 | .004 | .068 | .23 | |||
Rates of SR are compared with Fisher exact tests and cumulative incidences of CR by Gray tests.
SR indicates stereo resistant; CR, complete response; GI, gastrointestinal; AT, antitrypsin; and dw, dry weight.