Table 2

ISGS expression levels in HIV-1–infected MDMs measured by microarrays

GenBank accession no.Gene nameFold change (duplicate) arrayB value (duplicate)
NM_080657 Viperin 7.1 (6.8) 4.7 (3.2) 
NM_001547 IFIT-2 4.5 (4.5) 11.8 (11.7) 
NM_001548 IFIT-1 4.3 (4.1) 11.2 (11.5) 
NM_006820 IFI44L 2.9 (2.6) 4.9 (5.5) 
NM_002462 MX1 2.6 (2.6) 5.9 (5.2) 
NM_014314 RIGI (DDX58) 2.5 (2.1) 5.4 (6.7) 
NM_005101 ISG15 2.1 (1.9) 3.9 (2.7) 
NM_006187 2,5 OAS 3 1.9 (1.9) 1.5 (4.4) 
NM_006074 TRIM 22 1.9 (1.6) 0.3 (1.5) 
NM_007315 STAT-1 1.6 (1.6) 1.9 (2.1) 
GenBank accession no.Gene nameFold change (duplicate) arrayB value (duplicate)
NM_080657 Viperin 7.1 (6.8) 4.7 (3.2) 
NM_001547 IFIT-2 4.5 (4.5) 11.8 (11.7) 
NM_001548 IFIT-1 4.3 (4.1) 11.2 (11.5) 
NM_006820 IFI44L 2.9 (2.6) 4.9 (5.5) 
NM_002462 MX1 2.6 (2.6) 5.9 (5.2) 
NM_014314 RIGI (DDX58) 2.5 (2.1) 5.4 (6.7) 
NM_005101 ISG15 2.1 (1.9) 3.9 (2.7) 
NM_006187 2,5 OAS 3 1.9 (1.9) 1.5 (4.4) 
NM_006074 TRIM 22 1.9 (1.6) 0.3 (1.5) 
NM_007315 STAT-1 1.6 (1.6) 1.9 (2.1) 

MDMs from 4 donors were exposed to HIV-1 or to AT2–HIV-1 or mock infected for 5 days. Hybridizations to microarrays were performed for the comparisons of the effects of HIV-1, AT2–HIV-1, and mock treatments on the transcriptome of MDMs. The mean fold changes and B values for HIV-1/mock hybridization are shown here for each duplicate spot.

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