Staging of CML that we use in our practice
| Chronic phase |
| None of the criteria for accelerated or blastic phase |
| Accelerated phase |
| Blasts ≥ 15% in blood or BM |
| Blasts plus progranulocytes ≥ 30% in blood or BM |
| Basophilia ≥ 20% in blood or BM |
| Platelets < 100 × 109/L unrelated to therapy |
| Cytogenetic clonal evolution |
| Blast phase |
| ≥ 30% blasts in blood or BM |
| Extramedullary disease with localized immature blasts |
| Chronic phase |
| None of the criteria for accelerated or blastic phase |
| Accelerated phase |
| Blasts ≥ 15% in blood or BM |
| Blasts plus progranulocytes ≥ 30% in blood or BM |
| Basophilia ≥ 20% in blood or BM |
| Platelets < 100 × 109/L unrelated to therapy |
| Cytogenetic clonal evolution |
| Blast phase |
| ≥ 30% blasts in blood or BM |
| Extramedullary disease with localized immature blasts |