Features of NK receptors tested
| NKR . | CD . | Gene name . | Function . | Ligand . |
|---|---|---|---|---|
| p58.1 | CD158a,h | KIR2DL1 | Inhibitory | HLA-C |
| KIR2DS1 | Activating | |||
| p58.2 | CD158b,j | KIR2DL2 | Inhibitory | HLA-C/B |
| KIR2DS2 | Activating | |||
| p50.3 | CD158i | KIR2DS4 | Activating | HLA-C/A11 |
| p70 | CD158e | KIR3DS1 | Inhibitory | HLA-A/B |
| KIR3DL1 | Activating | |||
| NKG2A | CD159a | KLRC1 | Inhibitory | HLA-E |
| NKG2C | CD159c | KLRC2 | Activating | HLA-E |
| NKG2D | CD314 | KLRK1 | Activating | MICA/B |
| ULBP1 (bacteria) | ||||
| ILT2 | CD85j | LILRB1 | Inhibitory | HLA-B/C/G |
| UL18 (CMV) | ||||
| FcγRIIIa | CD16 | FCGR3A | Activating | Fc portion of IgG Ab |
| NKp46 | CD335 | NCR1 | Activating | ? |
| NKp44 | CD336 | NCR2 | Activating | ? |
| NKp30 | CD337 | NCR3 | Activating | ? |
| NKR . | CD . | Gene name . | Function . | Ligand . |
|---|---|---|---|---|
| p58.1 | CD158a,h | KIR2DL1 | Inhibitory | HLA-C |
| KIR2DS1 | Activating | |||
| p58.2 | CD158b,j | KIR2DL2 | Inhibitory | HLA-C/B |
| KIR2DS2 | Activating | |||
| p50.3 | CD158i | KIR2DS4 | Activating | HLA-C/A11 |
| p70 | CD158e | KIR3DS1 | Inhibitory | HLA-A/B |
| KIR3DL1 | Activating | |||
| NKG2A | CD159a | KLRC1 | Inhibitory | HLA-E |
| NKG2C | CD159c | KLRC2 | Activating | HLA-E |
| NKG2D | CD314 | KLRK1 | Activating | MICA/B |
| ULBP1 (bacteria) | ||||
| ILT2 | CD85j | LILRB1 | Inhibitory | HLA-B/C/G |
| UL18 (CMV) | ||||
| FcγRIIIa | CD16 | FCGR3A | Activating | Fc portion of IgG Ab |
| NKp46 | CD335 | NCR1 | Activating | ? |
| NKp44 | CD336 | NCR2 | Activating | ? |
| NKp30 | CD337 | NCR3 | Activating | ? |
NK indicates natural killer.