Polycomb group phosphopeptides identified in FLA2 and FLB1 leukemias
| Name . | Phosphopeptide sequence . | Phosphosites . | Ratio FLA2/FLB1* . | Confidence score . | Novel . |
|---|---|---|---|---|---|
| EZH2 | LPNNSpSRPpSTPTISVLESK | S363, S366 | 2.0 | 0.77, 0.87 | No/no |
| GRLPNNSpSRPpSTPTISVLESK | S363, S366 | 1.3 | 0.87, 0.88 | No/no | |
| LPNNSSRPSpTPTISVLESK | T367 | 1.1 | 0.42 | No | |
| ESSIIAPVPTEDVDpTPPR | T487 | 0.56 | 0.96 | No | |
| SUZ12 | ASMSEFLEpSEDGEVEQQR | S548 | 0.34 | 0.99 | No |
| LYFHSDTCLPLRPQEMEVDpSEDEKDPEWLR | S585 | 0.28 | 0.90 | No | |
| CBX8 | VDDKPSpSPGDSSK | S164 | 0.71 | 0.90 | No |
| BMI1 | KSpSLNGSSATSSG | S314 | 3.5 | 0.5 | Yes |
| PHC3 | KGGpSPGLESR | S281 | 1.4 | 1.00 | No |
| SFMBT1 | DAQTSSVpSDDENKPPpSPK | S764, S772 | NA | 0.95, 1.00 | No/no |
| KSSSpSSPTQSETPTPLPPDpTQTNK | S736, T751 | NA | 1.00, 1.00 | Yes/yes | |
| L3MBTL2 | SPpSPQLPLPIESIK | S687 | 1.4 | 0.84 | No |
| EEHQDISSLDRpSPpSPQLPLPIESIK | S685, S687 | NA | 1.00, 1.00 | No/no | |
| L3MBTL3 | LSGDTpSPPTTPSFPR | S605 | 3.5 | 0.82 | No |
| Name . | Phosphopeptide sequence . | Phosphosites . | Ratio FLA2/FLB1* . | Confidence score . | Novel . |
|---|---|---|---|---|---|
| EZH2 | LPNNSpSRPpSTPTISVLESK | S363, S366 | 2.0 | 0.77, 0.87 | No/no |
| GRLPNNSpSRPpSTPTISVLESK | S363, S366 | 1.3 | 0.87, 0.88 | No/no | |
| LPNNSSRPSpTPTISVLESK | T367 | 1.1 | 0.42 | No | |
| ESSIIAPVPTEDVDpTPPR | T487 | 0.56 | 0.96 | No | |
| SUZ12 | ASMSEFLEpSEDGEVEQQR | S548 | 0.34 | 0.99 | No |
| LYFHSDTCLPLRPQEMEVDpSEDEKDPEWLR | S585 | 0.28 | 0.90 | No | |
| CBX8 | VDDKPSpSPGDSSK | S164 | 0.71 | 0.90 | No |
| BMI1 | KSpSLNGSSATSSG | S314 | 3.5 | 0.5 | Yes |
| PHC3 | KGGpSPGLESR | S281 | 1.4 | 1.00 | No |
| SFMBT1 | DAQTSSVpSDDENKPPpSPK | S764, S772 | NA | 0.95, 1.00 | No/no |
| KSSSpSSPTQSETPTPLPPDpTQTNK | S736, T751 | NA | 1.00, 1.00 | Yes/yes | |
| L3MBTL2 | SPpSPQLPLPIESIK | S687 | 1.4 | 0.84 | No |
| EEHQDISSLDRpSPpSPQLPLPIESIK | S685, S687 | NA | 1.00, 1.00 | No/no | |
| L3MBTL3 | LSGDTpSPPTTPSFPR | S605 | 3.5 | 0.82 | No |
NA indicates not applicable.
Ratio normalized for changes in protein expression.