Univariable and multivariable analyses (COX regression) identifying independent risk factors for AML evolution of patients with MDS with thrombocytopenia
| Variable . | AML evolution . | |||
|---|---|---|---|---|
| Univariate Cox . | Multivariate Cox . | |||
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Age (≧60 y vs <60 y) | 0.949 (0.714-1.263) | .721 | ||
| Sex (male vs female) | 1.610 (1.209-2.144) | .001 | 1.350 (.893-2.042) | .155 |
| IPSS-R (higher risk vs lower risk) | 2.386 (2.047-2.780) | .000 | 4.692 (2.668-8.252) | .000 |
| WT1 (≥4.9% vs <4.9%) | 3.635 (2.716-4.865) | .000 | 1.663 (1.099-2.516) | .016 |
| PRAME (≥0.3% vs <0.3%) | 3.955 (2.211-7.074) | .000 | 1.879 (1.019-3.468) | .044 |
| Variable . | AML evolution . | |||
|---|---|---|---|---|
| Univariate Cox . | Multivariate Cox . | |||
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Age (≧60 y vs <60 y) | 0.949 (0.714-1.263) | .721 | ||
| Sex (male vs female) | 1.610 (1.209-2.144) | .001 | 1.350 (.893-2.042) | .155 |
| IPSS-R (higher risk vs lower risk) | 2.386 (2.047-2.780) | .000 | 4.692 (2.668-8.252) | .000 |
| WT1 (≥4.9% vs <4.9%) | 3.635 (2.716-4.865) | .000 | 1.663 (1.099-2.516) | .016 |
| PRAME (≥0.3% vs <0.3%) | 3.955 (2.211-7.074) | .000 | 1.879 (1.019-3.468) | .044 |