Table 4.

Outcomes of patients aged ≥60 years undergoing allogeneic transplantation during the pre-TOP and TOP multidisciplinary clinic eras

OutcomePre-TOP (2005-2012), n = 74TOP Initial (March 2013-2014)TOP Modern (2015-2018)
n = 27P*n = 58P*
Inpatient deaths during initial hospitalization, n (%) 13 (17.6) 0 (0) .018 0 (0) <.001 
Length of inpatient stay, median (IQR), d 19 (15-23) 15 (13-19) .045 14 (13-17) <.001 
Events by day 100, n/N (%) or n (%) 
 Discharge to nursing facility 11/61 (18) 1 (3.7) .096 1 (1.7) .0043 
 Readmission 36/61 (59) 16 (59.3) 27 (46.5) .20 
 Death 16 (21.6) 3 (11.1) .26 3 (5.2) .011 
Events by 1 y, % 
 OS 43.2 44.4 .66 70 <.001 
 NRM 43.2 37 18 .012 
OutcomePre-TOP (2005-2012), n = 74TOP Initial (March 2013-2014)TOP Modern (2015-2018)
n = 27P*n = 58P*
Inpatient deaths during initial hospitalization, n (%) 13 (17.6) 0 (0) .018 0 (0) <.001 
Length of inpatient stay, median (IQR), d 19 (15-23) 15 (13-19) .045 14 (13-17) <.001 
Events by day 100, n/N (%) or n (%) 
 Discharge to nursing facility 11/61 (18) 1 (3.7) .096 1 (1.7) .0043 
 Readmission 36/61 (59) 16 (59.3) 27 (46.5) .20 
 Death 16 (21.6) 3 (11.1) .26 3 (5.2) .011 
Events by 1 y, % 
 OS 43.2 44.4 .66 70 <.001 
 NRM 43.2 37 18 .012 

IQR, interquartile range.

*

Compared with pre-TOP cohort.

Excludes patients with death during initial inpatient transplant encounter.

Excludes 8 patients who received allogeneic transplant in 2018.

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