Summary of combination index values in three FLT3-ITD AML cell lines treated with LAM-003 in combination with those drugs used for AML
| . | Cell line . | ||
|---|---|---|---|
| Combination LAM-003 + . | MV-4-11 . | MOLM-13 . | MOLM-14 . |
| Daunorubicin | 0.6 | 0.9 | 0.8 |
| Cytarabine | 0.8 | 1.0 | 0.9 |
| Crenolanib | 0.7 | 0.9 | 1.0 |
| Sorafenib | 0.8 | 1.0 | 1.0 |
| Gilteritinib | 1.0 | 0.9 | 1.0 |
| Venetoclax | 0.7 | 0.3 | 0.6 |
| . | Cell line . | ||
|---|---|---|---|
| Combination LAM-003 + . | MV-4-11 . | MOLM-13 . | MOLM-14 . |
| Daunorubicin | 0.6 | 0.9 | 0.8 |
| Cytarabine | 0.8 | 1.0 | 0.9 |
| Crenolanib | 0.7 | 0.9 | 1.0 |
| Sorafenib | 0.8 | 1.0 | 1.0 |
| Gilteritinib | 1.0 | 0.9 | 1.0 |
| Venetoclax | 0.7 | 0.3 | 0.6 |