Currently identified acute myeloid leukemia antigens for immunotherapeutic targeting under preclinical or clinical study
| Target . | Monoclonal Antibody . | ADC . | Bispecific Antibody . | CAR T Cell . |
|---|---|---|---|---|
| CD7 | x | |||
| CD13 | x | x | ||
| CD33 | x | x | x | x |
| CD38 | x | x | ||
| CD44v6 | x | x | ||
| CD56 | x | x | ||
| FLT3 receptor (CD135) | x | x | x | |
| CD123 | x | x | x | x |
| CD174 (Lewis-Y) | x | |||
| CLEC12A (CLL-1, CD371) | x | x | x | |
| Folate receptor B | x | |||
| Mesothelin | x | |||
| NKG2DL | x | |||
| IL1RAP | x | x | x |
| Target . | Monoclonal Antibody . | ADC . | Bispecific Antibody . | CAR T Cell . |
|---|---|---|---|---|
| CD7 | x | |||
| CD13 | x | x | ||
| CD33 | x | x | x | x |
| CD38 | x | x | ||
| CD44v6 | x | x | ||
| CD56 | x | x | ||
| FLT3 receptor (CD135) | x | x | x | |
| CD123 | x | x | x | x |
| CD174 (Lewis-Y) | x | |||
| CLEC12A (CLL-1, CD371) | x | x | x | |
| Folate receptor B | x | |||
| Mesothelin | x | |||
| NKG2DL | x | |||
| IL1RAP | x | x | x |