Consensus-based recommendation for target platelet counts for surgery or medical therapy in adults
| Type of surgery . | Target platelet count, × 109/L . |
|---|---|
| Dental prophylaxis (descaling, deep cleaning) | ≥20 to 30 |
| Simple extractions | ≥30 |
| Complex extractions | ≥50 |
| Regional dental block | ≥30 |
| Minor surgery* | ≥50 |
| Major surgery | ≥80 |
| Major neurosurgery | ≥100 |
| Splenectomy | See “Subsequent therapy: surgical” |
| Obstetrics | See “Thrombocytopenia presenting during pregnancy” |
| Single antiplatelet agent or anticoagulant (ie, 1 antiplatelet agent, warfarin, or TSOAC) | ≥30 to 50 |
| Dual antiplatelet or anticoagulant (ie, 2 antiplatelet agents or 1 antiplatelet agent plus warfarin or TSOAC) | ≥50 to 70 |
| Type of surgery . | Target platelet count, × 109/L . |
|---|---|
| Dental prophylaxis (descaling, deep cleaning) | ≥20 to 30 |
| Simple extractions | ≥30 |
| Complex extractions | ≥50 |
| Regional dental block | ≥30 |
| Minor surgery* | ≥50 |
| Major surgery | ≥80 |
| Major neurosurgery | ≥100 |
| Splenectomy | See “Subsequent therapy: surgical” |
| Obstetrics | See “Thrombocytopenia presenting during pregnancy” |
| Single antiplatelet agent or anticoagulant (ie, 1 antiplatelet agent, warfarin, or TSOAC) | ≥30 to 50 |
| Dual antiplatelet or anticoagulant (ie, 2 antiplatelet agents or 1 antiplatelet agent plus warfarin or TSOAC) | ≥50 to 70 |
Evidence level IV. Adult patients with ITP considered to be at “typical” bleeding risk from surgery. Target platelet count depends on the clinical situation and urgency and need for procedure.
TSOAC, target-specific oral anticoagulants.
Cataract surgery with laser technique has no bleeding risk.