Considerations for use of auto-HCT and allo-HCT for indolent NHL
| Auto-HCT . | Allo-HCT . |
|---|---|
| Both of the following: | All of the following: |
| 1. Chemosensitive disease | 1. Ability to achieve low disease burden before transplant, may be following novel nonchemotherapy agents. |
| 2. Medically fit for high-dose therapy | 2. Appropriate donor available |
| AND one of the following: | 3. Medically fit/”younger” age |
| 1. Relapse within 24 mo of initial chemoimmunotherapy | AND one of the following: |
| 2. No more than third relapse | 1. Not eligible or have received prior auto-HCT |
| 3. Desire for time off therapy | 2. At least second relapse |
| 4. Short remission period after last therapy | 3. Short remission period after last therapy |
| Auto-HCT . | Allo-HCT . |
|---|---|
| Both of the following: | All of the following: |
| 1. Chemosensitive disease | 1. Ability to achieve low disease burden before transplant, may be following novel nonchemotherapy agents. |
| 2. Medically fit for high-dose therapy | 2. Appropriate donor available |
| AND one of the following: | 3. Medically fit/”younger” age |
| 1. Relapse within 24 mo of initial chemoimmunotherapy | AND one of the following: |
| 2. No more than third relapse | 1. Not eligible or have received prior auto-HCT |
| 3. Desire for time off therapy | 2. At least second relapse |
| 4. Short remission period after last therapy | 3. Short remission period after last therapy |