Risk factors for the development of CAT
| Risk factors . |
|---|
| Patient related |
| Personal history of VTE |
| Immobilization |
| Thrombophilia |
| Cardiovascular risk factors |
| Treatment related |
| Chemotherapy (immunomodulatory agent, angiogenesis agents, platinum-based therapy, anthracycline-containing therapy) |
| Hormonal therapy |
| Radiation therapy |
| Surgery |
| Central venous catheters |
| Cancer related |
| Cancer type |
| Cancer stage and histological grade |
| Time since cancer diagnosis |
| Tumor bulk leading to vascular compression |
| Biomarkers |
| Cytosis |
| D-dimer |
| P-selectin |
| Tissue factor-positive microvesicles |
| Elevation in plasminogen activator inhibitor-1 |
| Risk factors . |
|---|
| Patient related |
| Personal history of VTE |
| Immobilization |
| Thrombophilia |
| Cardiovascular risk factors |
| Treatment related |
| Chemotherapy (immunomodulatory agent, angiogenesis agents, platinum-based therapy, anthracycline-containing therapy) |
| Hormonal therapy |
| Radiation therapy |
| Surgery |
| Central venous catheters |
| Cancer related |
| Cancer type |
| Cancer stage and histological grade |
| Time since cancer diagnosis |
| Tumor bulk leading to vascular compression |
| Biomarkers |
| Cytosis |
| D-dimer |
| P-selectin |
| Tissue factor-positive microvesicles |
| Elevation in plasminogen activator inhibitor-1 |
Adapted from Ay et al19 with permission.