Comparison of the clinical characteristics of the training and validation cohorts
. | Training cohort, n = 49 . | Validation cohort, n = 124 . | . | ||
---|---|---|---|---|---|
n= . | n (%) . | n= . | n (%) . | P . | |
IHC classification | 49 | 124 | .66 | ||
PTCL-GATA3 | 15 (31) | 46 (37) | |||
PTCL-TBX21 | 31 (63) | 69 (56) | |||
Unclassified | 3 (6) | 9 (7) | |||
Sex | 42 | 100 | .54 | ||
Female | 17 (40) | 35 (35) | |||
Male | 25 (60) | 65 (65) | |||
Age, y | 39 | 98 | .04 | ||
≤60 | 13 (33) | 52 (53) | |||
>60 | 26 (67) | 46 (47) | |||
Stage | 17 | 73 | .22 | ||
I/II | 2 (12) | 20 (27) | |||
III/IV | 15 (88) | 53 (73) | |||
Extranodal sites | 6 | 74 | .66 | ||
≤1 | 4 (67) | 54 (73) | |||
>1 | 2 (33) | 20 (27) | |||
Serum LDH level | 14 | 67 | 1.00 | ||
Normal | 5 (36) | 25 (37) | |||
High | 9 (64) | 42 (63) | |||
IPI score | 13 | 63 | .24 | ||
Low: 0-2 | 5 (38) | 36 (57) | |||
High: 3-5 | 8 (62) | 27 (43) | |||
Treatment | 7 | 63 | .07 | ||
CHOP/CHOP-like | 4 (57) | 55 (87) | |||
Other | 2 (29) | 7 (11) | |||
None | 1 (14) | 1 (2) |
. | Training cohort, n = 49 . | Validation cohort, n = 124 . | . | ||
---|---|---|---|---|---|
n= . | n (%) . | n= . | n (%) . | P . | |
IHC classification | 49 | 124 | .66 | ||
PTCL-GATA3 | 15 (31) | 46 (37) | |||
PTCL-TBX21 | 31 (63) | 69 (56) | |||
Unclassified | 3 (6) | 9 (7) | |||
Sex | 42 | 100 | .54 | ||
Female | 17 (40) | 35 (35) | |||
Male | 25 (60) | 65 (65) | |||
Age, y | 39 | 98 | .04 | ||
≤60 | 13 (33) | 52 (53) | |||
>60 | 26 (67) | 46 (47) | |||
Stage | 17 | 73 | .22 | ||
I/II | 2 (12) | 20 (27) | |||
III/IV | 15 (88) | 53 (73) | |||
Extranodal sites | 6 | 74 | .66 | ||
≤1 | 4 (67) | 54 (73) | |||
>1 | 2 (33) | 20 (27) | |||
Serum LDH level | 14 | 67 | 1.00 | ||
Normal | 5 (36) | 25 (37) | |||
High | 9 (64) | 42 (63) | |||
IPI score | 13 | 63 | .24 | ||
Low: 0-2 | 5 (38) | 36 (57) | |||
High: 3-5 | 8 (62) | 27 (43) | |||
Treatment | 7 | 63 | .07 | ||
CHOP/CHOP-like | 4 (57) | 55 (87) | |||
Other | 2 (29) | 7 (11) | |||
None | 1 (14) | 1 (2) |
Not all data were available for all cases.
LDH, lactate dehydrogenase.