Comparison of advantages and disadvantages by conditioning intensity
| Reduced intensity/toxicity . | Myeloablative . |
|---|---|
| Pros | |
| • Decreased early and late side effects/organ toxicity | • Increased full donor chimerism |
| • May shorten duration of admission | • Decreased graft rejection |
| • May decrease number of blood transfusions required | |
| • May decrease cost of transplant | |
| • May be more easily expanded into low-income countries | |
| Cons | |
| • Increased mixed donor chimerism | • Increased early and late side effects/organ toxicity |
| • Increased graft rejection | • May increase duration of admission |
| • May increase number of blood transfusions required | |
| • May increase cost of transplant | |
| • May be less easily expanded into low income countries |
| Reduced intensity/toxicity . | Myeloablative . |
|---|---|
| Pros | |
| • Decreased early and late side effects/organ toxicity | • Increased full donor chimerism |
| • May shorten duration of admission | • Decreased graft rejection |
| • May decrease number of blood transfusions required | |
| • May decrease cost of transplant | |
| • May be more easily expanded into low-income countries | |
| Cons | |
| • Increased mixed donor chimerism | • Increased early and late side effects/organ toxicity |
| • Increased graft rejection | • May increase duration of admission |
| • May increase number of blood transfusions required | |
| • May increase cost of transplant | |
| • May be less easily expanded into low income countries |