Clinical characteristics and frequency of cytogenetic and diagnostic determinants of MM patients (N = 47)
| Characteristic . | n (%) or n/N (%) . |
|---|---|
| Age at diagnosis, y | |
| Median | 63 |
| Range | 40-87 |
| Sex | |
| Male | 33 (70) |
| Female | 14 (30) |
| PCs, % | |
| Median | 45 |
| Range | 4-100 |
| Immunoglobulin type | |
| IgG | 24 (51) |
| Non-IgG | 23 (49) |
| Light chain type | |
| κ | 26 (55) |
| λ | 21 (45) |
| Cytogenetics | |
| Standard risk | 32/47 (68) |
| High risk [1q amp, 17p del, t(4;14), or t(14;16)] | 15/47 (32) |
| Hyperdiploidy | 20/40 (50) |
| 13q del | 16/40 (40) |
| 1q amp | 12/44 (27) |
| t(11;14) | 7/38 (18) |
| t(4;14) | 3/41 (7) |
| t(14;16) | 2/42 (5) |
| 17p del | 0/26 (0) |
| ISS stage at diagnosis | |
| 1 | 16 (34) |
| 2 | 14 (30) |
| 3 | 13 (28) |
| ND | 4 (9) |
| Serum β2m ≥5.5 mg/L | 16/39 (41) |
| Serum albumin <3.5 g/L | 32/47 (68) |
| Bone lesions | 34/47 (72) |
| Anemia | 15/47 (32) |
| Renal insufficiency (serum creatinine levels >173 mmol/L) | 9/47 (19) |
| Characteristic . | n (%) or n/N (%) . |
|---|---|
| Age at diagnosis, y | |
| Median | 63 |
| Range | 40-87 |
| Sex | |
| Male | 33 (70) |
| Female | 14 (30) |
| PCs, % | |
| Median | 45 |
| Range | 4-100 |
| Immunoglobulin type | |
| IgG | 24 (51) |
| Non-IgG | 23 (49) |
| Light chain type | |
| κ | 26 (55) |
| λ | 21 (45) |
| Cytogenetics | |
| Standard risk | 32/47 (68) |
| High risk [1q amp, 17p del, t(4;14), or t(14;16)] | 15/47 (32) |
| Hyperdiploidy | 20/40 (50) |
| 13q del | 16/40 (40) |
| 1q amp | 12/44 (27) |
| t(11;14) | 7/38 (18) |
| t(4;14) | 3/41 (7) |
| t(14;16) | 2/42 (5) |
| 17p del | 0/26 (0) |
| ISS stage at diagnosis | |
| 1 | 16 (34) |
| 2 | 14 (30) |
| 3 | 13 (28) |
| ND | 4 (9) |
| Serum β2m ≥5.5 mg/L | 16/39 (41) |
| Serum albumin <3.5 g/L | 32/47 (68) |
| Bone lesions | 34/47 (72) |
| Anemia | 15/47 (32) |
| Renal insufficiency (serum creatinine levels >173 mmol/L) | 9/47 (19) |
ND, no data.