Patient characteristics
| Characteristic . | Type 1 VWD (N = 122) . |
|---|---|
| Age, mean ± SD, y | 47 ± 14 |
| Adult, n (%) | 120 (98) |
| Female, n (%) | 80 (66) |
| Blood group O, n (%) | 89 (73) |
| VWF gene mutation, n (%) | 48 (46)* |
| Historically lowest levels, IU/mL | |
| VWF:Ag | 0.33 [0.25-0.41] |
| VWF:Ab | 0.22 [0.14-0.26] |
| VWF:CB | 0.22 [0.16-0.30] |
| FVIII:C | 0.50 [0.38-0.63] |
| Levels immediately before desmopressin administration, IU/mL | |
| VWF:Ag | 0.44 [0.28-0.58] |
| VWF:Ab | 0.32 [0.22-0.52] |
| VWF:CB | 0.33 [0.18-0.62] |
| FVIII:C | 0.61 [0.48-0.86] |
| Bleeding score | 9 [5-14] |
| Characteristic . | Type 1 VWD (N = 122) . |
|---|---|
| Age, mean ± SD, y | 47 ± 14 |
| Adult, n (%) | 120 (98) |
| Female, n (%) | 80 (66) |
| Blood group O, n (%) | 89 (73) |
| VWF gene mutation, n (%) | 48 (46)* |
| Historically lowest levels, IU/mL | |
| VWF:Ag | 0.33 [0.25-0.41] |
| VWF:Ab | 0.22 [0.14-0.26] |
| VWF:CB | 0.22 [0.16-0.30] |
| FVIII:C | 0.50 [0.38-0.63] |
| Levels immediately before desmopressin administration, IU/mL | |
| VWF:Ag | 0.44 [0.28-0.58] |
| VWF:Ab | 0.32 [0.22-0.52] |
| VWF:CB | 0.33 [0.18-0.62] |
| FVIII:C | 0.61 [0.48-0.86] |
| Bleeding score | 9 [5-14] |
Data are presented as median [interquartile range], unless otherwise specified.
Genetic analysis was performed in 105 patients.