Baseline characteristics
| Variables . | Total (N = 215) . | Cohort 1, 2005-2010 (n = 118) . | Cohort 2, 2011-2016 (n = 97) . | P . |
|---|---|---|---|---|
| Age at diagnosis, median (range), y | 32 (19-72) | 32 (19-72) | 32 (19-68) | .59* |
| Age at auto-HCT, median (range), y | 35 (19-73) | 35 (20-73) | 34 (19-71) | .77* |
| Time from diagnosis to transplant, median (range), mo | 18 (5-240) | 21 (6-159) | 16 (5-240) | .03* |
| Time from transplant to relapse, median (range), mo | 6 (1-103) | 6 (1-103) | 6.5 (1-59) | .57* |
| Disease status before auto-HCT, n (%) | .002* | |||
| CR | 72 (34) | 28 (24) | 44 (45) | |
| PR | 121 (56) | 76 (64) | 45 (46) | |
| SD | 9 (4) | 6 (5) | 3 (3) | |
| PD | 13 (6) | 8 (7) | 5 (5) | |
| ECOG PS at auto-HCT, n (%) | .005† | |||
| 0 | 55 (42) | 32 (56) | 23 (31.5) | |
| 1-2 | 75 (58) | 25 (44) | 50 (68.5) | |
| Data missing | 85 | 61 | 24 | |
| PET status before auto-HCT, n (%) | .37† | |||
| Negative | 81 (41.5) | 41 (39) | 40 (45) | |
| Positive | 114 (58.5) | 65 (61) | 49 (55) | |
| Data missing | 20 | 12 | 8 | |
| Best response after auto-HCT, n (%) | .75* | |||
| CR | 114 (53) | 60 (51) | 54 (56) | |
| PR | 39 (18) | 29 (25) | 10 (10) | |
| SD | 17 (8) | 10 (8.5) | 7 (7) | |
| PD | 44 (20.5) | 19 (16) | 25 (26) | |
| Unknown | 1 (0.5) | 0 | 1 (1) | |
| Postrelapse lines of therapy, median (range), n | 2.0 (0.0-13.0) | 2.0 (0.0-13.0) | 2.0 (0.0-7.0) | .07* |
| Variables . | Total (N = 215) . | Cohort 1, 2005-2010 (n = 118) . | Cohort 2, 2011-2016 (n = 97) . | P . |
|---|---|---|---|---|
| Age at diagnosis, median (range), y | 32 (19-72) | 32 (19-72) | 32 (19-68) | .59* |
| Age at auto-HCT, median (range), y | 35 (19-73) | 35 (20-73) | 34 (19-71) | .77* |
| Time from diagnosis to transplant, median (range), mo | 18 (5-240) | 21 (6-159) | 16 (5-240) | .03* |
| Time from transplant to relapse, median (range), mo | 6 (1-103) | 6 (1-103) | 6.5 (1-59) | .57* |
| Disease status before auto-HCT, n (%) | .002* | |||
| CR | 72 (34) | 28 (24) | 44 (45) | |
| PR | 121 (56) | 76 (64) | 45 (46) | |
| SD | 9 (4) | 6 (5) | 3 (3) | |
| PD | 13 (6) | 8 (7) | 5 (5) | |
| ECOG PS at auto-HCT, n (%) | .005† | |||
| 0 | 55 (42) | 32 (56) | 23 (31.5) | |
| 1-2 | 75 (58) | 25 (44) | 50 (68.5) | |
| Data missing | 85 | 61 | 24 | |
| PET status before auto-HCT, n (%) | .37† | |||
| Negative | 81 (41.5) | 41 (39) | 40 (45) | |
| Positive | 114 (58.5) | 65 (61) | 49 (55) | |
| Data missing | 20 | 12 | 8 | |
| Best response after auto-HCT, n (%) | .75* | |||
| CR | 114 (53) | 60 (51) | 54 (56) | |
| PR | 39 (18) | 29 (25) | 10 (10) | |
| SD | 17 (8) | 10 (8.5) | 7 (7) | |
| PD | 44 (20.5) | 19 (16) | 25 (26) | |
| Unknown | 1 (0.5) | 0 | 1 (1) | |
| Postrelapse lines of therapy, median (range), n | 2.0 (0.0-13.0) | 2.0 (0.0-13.0) | 2.0 (0.0-7.0) | .07* |