Multivariate Cox regression analysis for cHL overall survival
| Description . | Point estimate . | Lower 95% CI . | Upper 95% CI . | P . |
|---|---|---|---|---|
| Cohort 1 vs cohort 2 | 2.300 | 1.148 | 4.606 | .02 |
| After Bv or CPI after relapse | 0.908 | 0.492 | 1.679 | .7594 |
| After allo-HCT after relapse | 0.860 | 0.426 | 1.738 | .6742 |
| Age at auto-HCT* | 1.489 | 1.183 | 1.875 | .0007 |
| Time to relapse from auto-HCT† | 0.596 | 0.474 | 0.749 | <.0001 |
| ECOG PS at auto-HCT 1-2 vs 0 | 1.222 | 0.663 | 2.252 | .5198 |
| Disease status at auto-HCT | ||||
| PD vs CR | 2.862 | 0.970 | 8.445 | .0569 |
| PR vs CR | 0.837 | 0.420 | 1.670 | .6143 |
| SD vs CR | 8.822 | 1.062 | 73.308 | .0439 |
| Description . | Point estimate . | Lower 95% CI . | Upper 95% CI . | P . |
|---|---|---|---|---|
| Cohort 1 vs cohort 2 | 2.300 | 1.148 | 4.606 | .02 |
| After Bv or CPI after relapse | 0.908 | 0.492 | 1.679 | .7594 |
| After allo-HCT after relapse | 0.860 | 0.426 | 1.738 | .6742 |
| Age at auto-HCT* | 1.489 | 1.183 | 1.875 | .0007 |
| Time to relapse from auto-HCT† | 0.596 | 0.474 | 0.749 | <.0001 |
| ECOG PS at auto-HCT 1-2 vs 0 | 1.222 | 0.663 | 2.252 | .5198 |
| Disease status at auto-HCT | ||||
| PD vs CR | 2.862 | 0.970 | 8.445 | .0569 |
| PR vs CR | 0.837 | 0.420 | 1.670 | .6143 |
| SD vs CR | 8.822 | 1.062 | 73.308 | .0439 |
ECOG PS, Eastern Cooperative Oncology Group performance status.
Age was used as a continuous covariate. The coefficient for age is per each 10-year increase in age after relapse.
Transplant-to-relapse time was used as a continuous covariate. The coefficient from transplant to relapse was per each doubling of the elapsed time.