Table 2. Aberrations significant for... | American Society of Hematology

Table 2.

Aberrations significant for early progression identified by Fisher exact test (P < .01)

Hg19 coordinates	Size, bp	Aberration	n (%)	Fisher exact test					Multivariate logistic model
				Early progression, n (%)		P	OR	95% CI	RC	SE	P	OR	95% CI
				Absent	Present	P	OR	95% CI	RC	SE	P	OR	95% CI
chr2p:58 999 505-59 187 207	187 703	Gain	49 (20)	36 (18)	19 (39)	.0038	2.80	(1.3, 5.8)	0.94	0.35	.007	2.55	(1.29, 5.03)
chr2p:59 467 016-59 825 992	358 977	Gain	52 (21)	36 (19)	19 (37)	.0086	2.50	(1.2, 5.1)
chr2p:59 846 982-60 471 823	624 842	Gain	54 (22)	35 (18)	20 (37)	.0054	2.61	(1.3, 5.3)
chr2p:57 275 499-59 260 307*	1 984 809	cnLOH	8 (3)	49 (21)	6 (75)	.0020	11.36	(2.0, 118.5)	2.39	0.85	.005	10.9	(2.08, 57.2)

Hg19 coordinates	Size, bp	Aberration	n (%)	Fisher exact test					Multivariate logistic model
				Early progression, n (%)		P	OR	95% CI	RC	SE	P	OR	95% CI
				Absent	Present	P	OR	95% CI	RC	SE	P	OR	95% CI
chr2p:58 999 505-59 187 207	187 703	Gain	49 (20)	36 (18)	19 (39)	.0038	2.80	(1.3, 5.8)	0.94	0.35	.007	2.55	(1.29, 5.03)
chr2p:59 467 016-59 825 992	358 977	Gain	52 (21)	36 (19)	19 (37)	.0086	2.50	(1.2, 5.1)
chr2p:59 846 982-60 471 823	624 842	Gain	54 (22)	35 (18)	20 (37)	.0054	2.61	(1.3, 5.3)
chr2p:57 275 499-59 260 307*	1 984 809	cnLOH	8 (3)	49 (21)	6 (75)	.0020	11.36	(2.0, 118.5)	2.39	0.85	.005	10.9	(2.08, 57.2)

OR, odds ratio; RC, regression coefficient; SE, standard error.

The last row denotes distal 2p cnLOH, which encompasses chr2p:57 275 499-59 260 307.