Multivariable analysis for factors that have an impact on EFS in patients who achieved MRD-negative CR, adjusted for HCT after CAR T-cell therapy as a time-dependent covariate
Variable . | Multivariable analysis . | P . | |
---|---|---|---|
HR . | 95% CI . | ||
LDH prelymphodepletion (per 100 U/L increment) | 1.39 | 1.11-1.73 | .004 |
Platelets prelymphodepletion (per 50 000/μL increment) | 0.74 | 0.53-1.03 | .069 |
Fludarabine added to lymphodepletion | 0.25 | 0.15-0.78 | .003 |
HCT after CAR T-cell therapy | 0.39 | 0.13-1.15 | .088 |
Variable . | Multivariable analysis . | P . | |
---|---|---|---|
HR . | 95% CI . | ||
LDH prelymphodepletion (per 100 U/L increment) | 1.39 | 1.11-1.73 | .004 |
Platelets prelymphodepletion (per 50 000/μL increment) | 0.74 | 0.53-1.03 | .069 |
Fludarabine added to lymphodepletion | 0.25 | 0.15-0.78 | .003 |
HCT after CAR T-cell therapy | 0.39 | 0.13-1.15 | .088 |