Characteristics of CLL patients included in CAR T-cell trial NCT01029366 or NCT01747486, and included in this study
| No. . | Clinical protocol . | Sex . | Age, y . | Overall response . | MRD (apheresis) . | Infused CAR T cells . |
|---|---|---|---|---|---|---|
| 1 | NCT01747486 | Male | 56 | CR | 2.96E+11 | 1.78E+08 |
| 2 | NCT01747486 | Male | 51 | CR | 1.02E+03 | 2.46E+07 |
| 3 | NCT01747486 | Male | 63 | CR | 6.57E+08 | 2.52E+07 |
| 4 | NCT01747486 | Male | 62 | CR | 5.57E+09 | 2.53E+08 |
| 5 | NCT01747486 | Female | 60 | CR | 2.51E+10 | 2.65E+08 |
| 6 | NCT01747486 | Male | 60 | NR | 2.95E+10 | 3.06E+08 |
| 7 | NCT01747486 | Male | 63 | NR | 2.14E+11 | 1.23E+07 |
| 8 | NCT01747486 | Female | 59 | NR | 1.11E+09 | 1.38E+07 |
| 9 | NCT01747486 | Male | 62 | NR | 6.65E+10 | 7.00E+07 |
| 10 | NCT01747486 | Female | 54 | NR | 1.93E+10 | 2.69E+08 |
| 11 | NCT01747486 | Male | 55 | NR | 8.95E+09 | 3.86E+07 |
| 12 | NCT01747486 | Male | 72 | NR | 2.16E+10 | 2.55E+07 |
| 13 | NCT01747486 | Female | 58 | NR | 6.00E+09 | 3.18E+06 |
| 14 | NCT01747486 | Male | 68 | NR | 8.42E+09 | 1.92E+08 |
| 15 | NCT01747486 | Male | 54 | NR | 1.64E+09 | 2.18E+07 |
| 16 | NCT01747486 | Female | 64 | NR | 1.12E+11 | 1.93E+07 |
| 17 | NCT01747486 | Female | 59 | NR | 5.77E+04 | 1.00E+09 |
| 18 | NCT01747486 | Male | 69 | NR | 3.44E+04 | 5.00E+08 |
| 19 | NCT01747486 | Male | 76 | NR | 1.62E+10 | 2.88E+08 |
| 20 | NCT01747486 | Male | 67 | NR | 1.53E+08 | 1.08E+07 |
| 21 | NCT01747486 | Female | 61 | NR | 3.60E+10 | 1.83E+07 |
| 22 | NCT01029366 | Male | 59 | CR | 2.00E+05 | 1.70E+08 |
| 23 | NCT01029366 | Male | 78 | CR | 2.55E+10 | 9.36E+08 |
| 24 | NCT01029366 | Male | 78 | NR | 2.64E+10 | 1.03E+08 |
| 25 | NCT01029366 | Female | 64 | NR | 5.45E+10 | 2.77E+08 |
| 26 | NCT01029366 | Female | 75 | NR | 1.08E+11 | 2.71E+08 |
| 27 | NCT01029366 | Male | 70 | NR | 3.20E+11 | 1.56E+08 |
| No. . | Clinical protocol . | Sex . | Age, y . | Overall response . | MRD (apheresis) . | Infused CAR T cells . |
|---|---|---|---|---|---|---|
| 1 | NCT01747486 | Male | 56 | CR | 2.96E+11 | 1.78E+08 |
| 2 | NCT01747486 | Male | 51 | CR | 1.02E+03 | 2.46E+07 |
| 3 | NCT01747486 | Male | 63 | CR | 6.57E+08 | 2.52E+07 |
| 4 | NCT01747486 | Male | 62 | CR | 5.57E+09 | 2.53E+08 |
| 5 | NCT01747486 | Female | 60 | CR | 2.51E+10 | 2.65E+08 |
| 6 | NCT01747486 | Male | 60 | NR | 2.95E+10 | 3.06E+08 |
| 7 | NCT01747486 | Male | 63 | NR | 2.14E+11 | 1.23E+07 |
| 8 | NCT01747486 | Female | 59 | NR | 1.11E+09 | 1.38E+07 |
| 9 | NCT01747486 | Male | 62 | NR | 6.65E+10 | 7.00E+07 |
| 10 | NCT01747486 | Female | 54 | NR | 1.93E+10 | 2.69E+08 |
| 11 | NCT01747486 | Male | 55 | NR | 8.95E+09 | 3.86E+07 |
| 12 | NCT01747486 | Male | 72 | NR | 2.16E+10 | 2.55E+07 |
| 13 | NCT01747486 | Female | 58 | NR | 6.00E+09 | 3.18E+06 |
| 14 | NCT01747486 | Male | 68 | NR | 8.42E+09 | 1.92E+08 |
| 15 | NCT01747486 | Male | 54 | NR | 1.64E+09 | 2.18E+07 |
| 16 | NCT01747486 | Female | 64 | NR | 1.12E+11 | 1.93E+07 |
| 17 | NCT01747486 | Female | 59 | NR | 5.77E+04 | 1.00E+09 |
| 18 | NCT01747486 | Male | 69 | NR | 3.44E+04 | 5.00E+08 |
| 19 | NCT01747486 | Male | 76 | NR | 1.62E+10 | 2.88E+08 |
| 20 | NCT01747486 | Male | 67 | NR | 1.53E+08 | 1.08E+07 |
| 21 | NCT01747486 | Female | 61 | NR | 3.60E+10 | 1.83E+07 |
| 22 | NCT01029366 | Male | 59 | CR | 2.00E+05 | 1.70E+08 |
| 23 | NCT01029366 | Male | 78 | CR | 2.55E+10 | 9.36E+08 |
| 24 | NCT01029366 | Male | 78 | NR | 2.64E+10 | 1.03E+08 |
| 25 | NCT01029366 | Female | 64 | NR | 5.45E+10 | 2.77E+08 |
| 26 | NCT01029366 | Female | 75 | NR | 1.08E+11 | 2.71E+08 |
| 27 | NCT01029366 | Male | 70 | NR | 3.20E+11 | 1.56E+08 |
MRD, minimal residual disease.