Correlation between treatment dose levels and response of patients in the Würzburg cohort (N = 38)
| . | No. of patients treated . | Dose . | |
|---|---|---|---|
| ≥60 µg/m2 per d . | <60 µg/m2 per d . | ||
| Response, n (%) | |||
| CR | 10 (26.3) | 9 (36.0) | 1 (7.7) |
| PR | 7 (18.4) | 7 (28.0) | 0 |
| SD | 7 (18.4) | 2 (8.0) | 5 (38.5) |
| PD | 12 (31.6) | 6 (24.0) | 6 (42.2) |
| NA | 2 (5.3) | 1 (4.0) | 1 (7.7) |
| ORR*n (%) | |||
| FL | 10 (55.6) | 9 | 1 |
| MCL | 6 (46.2) | 6 | 0 |
| DLBCL | 1 (20.0) | 1 | 0 |
| Others | 0 (0) | 0 | 0 |
| Survival | |||
| OS, y | 4.6 | 5.8 | 1.1 |
| PFS | 6.7 mo | 1.5 y | 32 d |
| TFS | 7.6 mo | 3.5 y | 37 d |
| . | No. of patients treated . | Dose . | |
|---|---|---|---|
| ≥60 µg/m2 per d . | <60 µg/m2 per d . | ||
| Response, n (%) | |||
| CR | 10 (26.3) | 9 (36.0) | 1 (7.7) |
| PR | 7 (18.4) | 7 (28.0) | 0 |
| SD | 7 (18.4) | 2 (8.0) | 5 (38.5) |
| PD | 12 (31.6) | 6 (24.0) | 6 (42.2) |
| NA | 2 (5.3) | 1 (4.0) | 1 (7.7) |
| ORR*n (%) | |||
| FL | 10 (55.6) | 9 | 1 |
| MCL | 6 (46.2) | 6 | 0 |
| DLBCL | 1 (20.0) | 1 | 0 |
| Others | 0 (0) | 0 | 0 |
| Survival | |||
| OS, y | 4.6 | 5.8 | 1.1 |
| PFS | 6.7 mo | 1.5 y | 32 d |
| TFS | 7.6 mo | 3.5 y | 37 d |
Data are shown in absolute numbers and as relative (%) quantities.
NA, not applicable; PD, progressive disease; SD, stable disease.
ORR: CR and PR.