Patient characteristics
Variables . | Number of patients . |
---|---|
Median age, y | 61 (range, 41-68) |
Male:female | 2:1 |
ECOG performance status >1 | 7 |
High lactic dehydrogenase serum level | 6 |
High CSF protein concentration* | 6 |
Involvement of deep areas | 5 |
IELSG risk score | |
Low | 1 |
Intermediate | 9 |
High | 2 |
Intraocular disease | 1 |
Meningeal dissemination | 0 |
Previous lines | |
Previous lines ≥2 | 7 |
Previous ASCT | 3 |
Previous WBRT | 3 |
Both ASCT + WBRT | 4 |
Refractory to previous lines | 7 |
Variables . | Number of patients . |
---|---|
Median age, y | 61 (range, 41-68) |
Male:female | 2:1 |
ECOG performance status >1 | 7 |
High lactic dehydrogenase serum level | 6 |
High CSF protein concentration* | 6 |
Involvement of deep areas | 5 |
IELSG risk score | |
Low | 1 |
Intermediate | 9 |
High | 2 |
Intraocular disease | 1 |
Meningeal dissemination | 0 |
Previous lines | |
Previous lines ≥2 | 7 |
Previous ASCT | 3 |
Previous WBRT | 3 |
Both ASCT + WBRT | 4 |
Refractory to previous lines | 7 |
ECOG, Eastern Cooperative Oncology Group; IELSG, International Extranodal Lymphoma Study Group.
Lumbar puncture was contraindicated in 3 patients; CSF protein concentration was considered as unfavorable feature in IELSG risk score in these patients.