Univariate and multivariate analysis of DFS and OS
| . | Disease-free survival . | Overall survival . | ||||
|---|---|---|---|---|---|---|
| Univariate analysis . | Multivariate analysis . | Univariate analysis . | Multivariate analysis . | |||
| P value . | P value3-150 . | Pvalue3-151 . | P value . | P value3-152 . | Pvalue3-153 . | |
| Achievement of CR (CR vs no CR) | — | — | — | <.0001 | <.0001 | <.0001 |
| Age | .02 | .03 | .02 | <.0001 | NS | NS |
| Cytogenetics (good vs intermediate + poor) | .01 | .04 | .04 | .005 | NS | NS |
| WHO performance status (0-1 vs 2-4) | NS | — | — | .01 | NS | NS |
| WBC count at diagnosis | NS | — | — | NS | — | — |
| LDH level | NS | — | — | NS | — | — |
| Pgp expression | .02 | NS | NS | .0007 | NS | NS |
| JC-1 (green fluorescence) + versus − (R vs I + S) | .02 | .03 | — | .0002 | .0002 | — |
| JC-1 (both green and red fluorescence) + versus − (R + I vs S) | .01 | — | .01 | .001 | — | .02 |
| Treatment (graft vs chemotherapy alone) | NS | — | — | .001 | NS | NS |
| . | Disease-free survival . | Overall survival . | ||||
|---|---|---|---|---|---|---|
| Univariate analysis . | Multivariate analysis . | Univariate analysis . | Multivariate analysis . | |||
| P value . | P value3-150 . | Pvalue3-151 . | P value . | P value3-152 . | Pvalue3-153 . | |
| Achievement of CR (CR vs no CR) | — | — | — | <.0001 | <.0001 | <.0001 |
| Age | .02 | .03 | .02 | <.0001 | NS | NS |
| Cytogenetics (good vs intermediate + poor) | .01 | .04 | .04 | .005 | NS | NS |
| WHO performance status (0-1 vs 2-4) | NS | — | — | .01 | NS | NS |
| WBC count at diagnosis | NS | — | — | NS | — | — |
| LDH level | NS | — | — | NS | — | — |
| Pgp expression | .02 | NS | NS | .0007 | NS | NS |
| JC-1 (green fluorescence) + versus − (R vs I + S) | .02 | .03 | — | .0002 | .0002 | — |
| JC-1 (both green and red fluorescence) + versus − (R + I vs S) | .01 | — | .01 | .001 | — | .02 |
| Treatment (graft vs chemotherapy alone) | NS | — | — | .001 | NS | NS |
NS indicates not significant.
In this model, we have included age, cytogenetics, Pgp expression, and JC-1 (R vs I + S).
In this model, we have included age, cytogenetics, Pgp expression, and JC-1 (R + I vs S).
In this model, we have included achievement of CR, age, cytogenetics, WHO performance status, consolidation treatment, Pgp expression, and JC-1 (R vs I + S).
In this model, we have included achievement of CR, age, cytogenetics, WHO performance status, consolidation treatment, Pgp expression, and JC-1 (R + I vs S).