Table 3. Urine concentrating ability in... | American Society of Hematology

Table 3.

Urine concentrating ability in sickle transgenic mice

	β^S %	α^H%	γ% >9 wk	Urine concentrate (mOsm)
C57BL				3147 ± 653^3-150
CONTROL	—	—	—	1688 ± 233^3-151
C57BL Hbb^th-1//Hbb^th-1
THAL	—	—	—	2820 ± 405^3-150
α2β^Sγ^(G203)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
NY1KO γM	80	100	20	1176 ± 127^3-151^b
α2β^Sγ^(G100)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
NY1KO γH	60	100	40	3285 ± 368^3-150,^3-a
α1^Gγ^Aγδβ^SHba⁰//Hba⁰Hbb⁰//Hbb⁰
BERK	>99	100	<1	898 ± 226^3-151^b
α1^Gγ^Aγδβ^Sγ^(G203)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
BERK γM	79	100	21	1710 ± 474^3-151,^3-a

	β^S %	α^H%	γ% >9 wk	Urine concentrate (mOsm)
C57BL				3147 ± 653^3-150
CONTROL	—	—	—	1688 ± 233^3-151
C57BL Hbb^th-1//Hbb^th-1
THAL	—	—	—	2820 ± 405^3-150
α2β^Sγ^(G203)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
NY1KO γM	80	100	20	1176 ± 127^3-151^b
α2β^Sγ^(G100)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
NY1KO γH	60	100	40	3285 ± 368^3-150,^3-a
α1^Gγ^Aγδβ^SHba⁰//Hba⁰Hbb⁰//Hbb⁰
BERK	>99	100	<1	898 ± 226^3-151^b
α1^Gγ^Aγδβ^Sγ^(G203)Hba⁰//Hba⁰Hbb⁰//Hbb⁰
BERK γM	79	100	21	1710 ± 474^3-151,^3-a

Mean ± SD. The statistics were calculated using the program StatGraphics.

24-hour water deprivation.

8-hour water deprivation.

Not statistically different from C57BL; b,P < .01 versus C57BL.