Results of experiments indicating that autocrine IL-6 production parallels IL-6–independent myeloma cell growth
| Myeloma cell clone/line . | Tritium-thymidine uptake . | Stimulation index . | IL-6+ myeloma cells (%) . | |
|---|---|---|---|---|
| Baseline . | With IL-6 . | |||
| MCC-1 | 6250 | 29 800 | 4.8 | 27 |
| MCC-2 | 52 136 | 59 358 | < 3 | 100 |
| MCC-3 | 7598 | 12 516 | < 3 | 80 |
| MCC-4 | 2635 | 28 419 | 10.1 | 10 |
| MCC-5 | 11841 | 22 317 | < 3 | 77 |
| MCC-6 | 1861 | 43 816 | 22.4 | 5 |
| U-266 | 8563 | 42 815 | 5.0 | 43 |
| IM-9 | 53 693 | 67 079 | < 3 | 100 |
| Myeloma cell clone/line . | Tritium-thymidine uptake . | Stimulation index . | IL-6+ myeloma cells (%) . | |
|---|---|---|---|---|
| Baseline . | With IL-6 . | |||
| MCC-1 | 6250 | 29 800 | 4.8 | 27 |
| MCC-2 | 52 136 | 59 358 | < 3 | 100 |
| MCC-3 | 7598 | 12 516 | < 3 | 80 |
| MCC-4 | 2635 | 28 419 | 10.1 | 10 |
| MCC-5 | 11841 | 22 317 | < 3 | 77 |
| MCC-6 | 1861 | 43 816 | 22.4 | 5 |
| U-266 | 8563 | 42 815 | 5.0 | 43 |
| IM-9 | 53 693 | 67 079 | < 3 | 100 |