Patient characteristics (N = 50)
| Characteristics . | Values . |
|---|---|
| Age ≥75 y, n (%) | 26 (52) |
| Median age (range), y | 75 (66-84) |
| Male, n (%) | 29 (58) |
| ECOG status, n (%) | |
| 0 to 1 | 43 (86) |
| 2 | 7 (14) |
| AML type, n (%) | |
| De novo | 33 (66) |
| Secondary | 12 (24) |
| MDS | 10 (20) |
| MPN | 2 (4) |
| Therapy-related | 5 (10) |
| AML FAB classification, n (%) | |
| M0 | 5 (10) |
| M1 | 7 (14) |
| M2 | 19 (38) |
| M4 | 8 (16) |
| M5 | 3 (6) |
| M6 | 2 (4) |
| Unknown | 6 (12) |
| Cytogenetic risk group, n (%) | |
| Intermediate | 27 (54) |
| Cytogenetically normal | 21 (42) |
| Cytogenetically abnormal | 6 (12) |
| High | 21 (42) |
| Median peripheral blood blasts (range), % | 2 (0-77) |
| Median BM blasts (range), % | 40 (20-89) |
| Median hemoglobin (range), g/dL | 9.3 (6.5-15.3) |
| Median platelets (range), ×109/L | 45.5 (9-639) |
| Median white blood cell count (range), ×109/L | 2.6 (0.8-29.6) |
| Median ANC (range), ×109/L | 0.58 (0-6.8) |
| Median creatinine (range), mg/dL | 0.9 (0.5-1.6) |
| Median bilirubin (range), mg/dL | 0.6 (0.2-5) |
| Characteristics . | Values . |
|---|---|
| Age ≥75 y, n (%) | 26 (52) |
| Median age (range), y | 75 (66-84) |
| Male, n (%) | 29 (58) |
| ECOG status, n (%) | |
| 0 to 1 | 43 (86) |
| 2 | 7 (14) |
| AML type, n (%) | |
| De novo | 33 (66) |
| Secondary | 12 (24) |
| MDS | 10 (20) |
| MPN | 2 (4) |
| Therapy-related | 5 (10) |
| AML FAB classification, n (%) | |
| M0 | 5 (10) |
| M1 | 7 (14) |
| M2 | 19 (38) |
| M4 | 8 (16) |
| M5 | 3 (6) |
| M6 | 2 (4) |
| Unknown | 6 (12) |
| Cytogenetic risk group, n (%) | |
| Intermediate | 27 (54) |
| Cytogenetically normal | 21 (42) |
| Cytogenetically abnormal | 6 (12) |
| High | 21 (42) |
| Median peripheral blood blasts (range), % | 2 (0-77) |
| Median BM blasts (range), % | 40 (20-89) |
| Median hemoglobin (range), g/dL | 9.3 (6.5-15.3) |
| Median platelets (range), ×109/L | 45.5 (9-639) |
| Median white blood cell count (range), ×109/L | 2.6 (0.8-29.6) |
| Median ANC (range), ×109/L | 0.58 (0-6.8) |
| Median creatinine (range), mg/dL | 0.9 (0.5-1.6) |
| Median bilirubin (range), mg/dL | 0.6 (0.2-5) |
ANC, absolute neutrophil count; FAB, French-American-British; MPN, myeloproliferative neoplasm.