RNAseq analysis of CD34+ cell genes that are altered by DWJM
Effect of DWJM . | Genes of HSPCs . | Log2 (fold change) . | Adjusted P . |
---|---|---|---|
Upregulation | GATA2 | 1.50 | 1.61e-28 |
CDKN1A | 1.42 | 5.70e-11 | |
TAL1 | 1.20 | 2.05e-03 | |
MECOM | 1.18 | 1.72e-01 | |
ITGβ3 | 0.94 | 3.39e-02 | |
ITGA2B | 0.86 | 2.47e-09 | |
NTRK1 | 0.78 | 2.40e-02 | |
PRKCQ | 0.63 | 1.01e-02 | |
Downregulation | IL6R | −0.73 | 1.49e-03 |
MPO | −1.24 | 7.34e-03 | |
MIR223 | −1.31 | 8.60e-06 | |
CHI3L1 | −1.36 | 2.52e-03 | |
CSF1R | −1.97 | 3.20e-18 | |
CTSG | −2.00 | 1.64e-07 | |
CST7 | −2.38 | 2.14e-40 |
Effect of DWJM . | Genes of HSPCs . | Log2 (fold change) . | Adjusted P . |
---|---|---|---|
Upregulation | GATA2 | 1.50 | 1.61e-28 |
CDKN1A | 1.42 | 5.70e-11 | |
TAL1 | 1.20 | 2.05e-03 | |
MECOM | 1.18 | 1.72e-01 | |
ITGβ3 | 0.94 | 3.39e-02 | |
ITGA2B | 0.86 | 2.47e-09 | |
NTRK1 | 0.78 | 2.40e-02 | |
PRKCQ | 0.63 | 1.01e-02 | |
Downregulation | IL6R | −0.73 | 1.49e-03 |
MPO | −1.24 | 7.34e-03 | |
MIR223 | −1.31 | 8.60e-06 | |
CHI3L1 | −1.36 | 2.52e-03 | |
CSF1R | −1.97 | 3.20e-18 | |
CTSG | −2.00 | 1.64e-07 | |
CST7 | −2.38 | 2.14e-40 |
A positive value indicates an upregulation, whereas a negative value indicates a downregulation of genes in CD34+ UCB cells by DWJM. Genes upregulated by DWJM are labeled in bold.