Laboratory parameters in the SCCRIP BMD cohort
| Variable . | All (N = 306) . | Female (n = 153) . | Male (n = 153) . | |||
|---|---|---|---|---|---|---|
| Normal BMD (n = 250 [81.7%]) . | Low BMD (n = 56 [18.3%]) . | Normal BMD (n = 128 [83.7%]) . | Low BMD (n = 25 [16.3%]) . | Normal BMD (n = 122 [79.7%]) . | Low BMD (n = 31 [20.3%]) . | |
| WBC, ×109/L | 9.3 ± 4.03 | 9.6 ± 3.71 | 9.0 ± 3.92 | 9.5 ± 4.37 | 9.7 ± 4.13 | 9.6 ± 3.14 |
| Hemoglobin, g/dL | 10.2 ± 1.60* | 9.5 ± 1.45* | 10.0 ± 1.45 | 9.5 ± 1.31 | 10.3 ± 1.74* | 9.5 ± 1.58* |
| Platelets, ×109/L | 343.5 ± 174.97 | 383.0 ± 182.02 | 323.4 ± 158.85 | 388.0 ± 196.77 | 363.9 ± 188.42 | 378.8 ± 172.07 |
| LDH, U/L | 411.0 ± 177.51 | 420.9 ± 164.17 | 374.8 ± 149.96 | 369.9 ± 143.80 | 449.9 ± 196.30 | 461.6 ± 170.24 |
| Total bilirubin, mg/dL | 1.9 ± 1.28* | 2.6 ± 1.62* | 1.7 ± 1.09 | 2.4 ± 1.72 | 2.0 ± 1.44* | 2.7 ± 1.55* |
| Indirect bilirubin, mg/dL | 2.1 ± 1.21* | 2.6 ± 1.48* | 2.0 ± 0.96 | 2.6 ± 1.58 | 2.1 ± 1.41* | 2.6 ± 1.44* |
| Fetal hemoglobin, % | 15.3 ± 10.64 | 13.1 ± 7.82 | 15.0 ± 10.85 | 11.7 ± 7.64 | 15.6 ± 10.46 | 14.2 ± 7.95 |
| Albumin, g/dL | 4.4 ± 0.27 | 4.4 ± 0.31 | 4.4 ± 0.27 | 4.5 ± 0.25 | 4.5 ± 0.28 | 4.4 ± 0.35 |
| ALP, U/L | 158.4 ± 72.09 | 142.5 ± 59.77 | 140.4 ± 72.30 | 128.1 ± 62.48 | 176.4 ± 67.50 | 154.3 ± 55.81 |
| AST/SGOT, U/L | 34.8 ± 15.17 | 34.8 ± 12.29 | 32.1 ± 15.14 | 31.4 ± 11.22 | 37.5 ± 14.78 | 37.6 ± 12.62 |
| Calcium, mg/dL | 9.5 ± 0.37* | 9.4 ± 0.31* | 9.4 ± 0.38 | 9.4 ± 0.28 | 9.5 ± 0.35* | 9.3 ± 0.34* |
| Creatinine, mg/dL | 0.5 ± 0.16 | 0.5 ± 0.13 | 0.5 ± 0.15 | 0.5 ± 0.11 | 0.5 ± 0.18 | 0.5 ± 0.15 |
| BUN, mg/dL | 7.5 ± 2.67 | 7.0 ± 2.07 | 7.2 ± 2.16 | 6.7 ± 2.26 | 7.9 ± 3.08 | 7.1 ± 1.93 |
| Vitamin D, ng/mL | 25.0 ± 11.13 | 22.5 ± 8.35 | 24.8 ± 10.85* | 19.6 ± 8.17* | 25.3 ± 11.46 | 25.2 ± 7.70 |
| Variable . | All (N = 306) . | Female (n = 153) . | Male (n = 153) . | |||
|---|---|---|---|---|---|---|
| Normal BMD (n = 250 [81.7%]) . | Low BMD (n = 56 [18.3%]) . | Normal BMD (n = 128 [83.7%]) . | Low BMD (n = 25 [16.3%]) . | Normal BMD (n = 122 [79.7%]) . | Low BMD (n = 31 [20.3%]) . | |
| WBC, ×109/L | 9.3 ± 4.03 | 9.6 ± 3.71 | 9.0 ± 3.92 | 9.5 ± 4.37 | 9.7 ± 4.13 | 9.6 ± 3.14 |
| Hemoglobin, g/dL | 10.2 ± 1.60* | 9.5 ± 1.45* | 10.0 ± 1.45 | 9.5 ± 1.31 | 10.3 ± 1.74* | 9.5 ± 1.58* |
| Platelets, ×109/L | 343.5 ± 174.97 | 383.0 ± 182.02 | 323.4 ± 158.85 | 388.0 ± 196.77 | 363.9 ± 188.42 | 378.8 ± 172.07 |
| LDH, U/L | 411.0 ± 177.51 | 420.9 ± 164.17 | 374.8 ± 149.96 | 369.9 ± 143.80 | 449.9 ± 196.30 | 461.6 ± 170.24 |
| Total bilirubin, mg/dL | 1.9 ± 1.28* | 2.6 ± 1.62* | 1.7 ± 1.09 | 2.4 ± 1.72 | 2.0 ± 1.44* | 2.7 ± 1.55* |
| Indirect bilirubin, mg/dL | 2.1 ± 1.21* | 2.6 ± 1.48* | 2.0 ± 0.96 | 2.6 ± 1.58 | 2.1 ± 1.41* | 2.6 ± 1.44* |
| Fetal hemoglobin, % | 15.3 ± 10.64 | 13.1 ± 7.82 | 15.0 ± 10.85 | 11.7 ± 7.64 | 15.6 ± 10.46 | 14.2 ± 7.95 |
| Albumin, g/dL | 4.4 ± 0.27 | 4.4 ± 0.31 | 4.4 ± 0.27 | 4.5 ± 0.25 | 4.5 ± 0.28 | 4.4 ± 0.35 |
| ALP, U/L | 158.4 ± 72.09 | 142.5 ± 59.77 | 140.4 ± 72.30 | 128.1 ± 62.48 | 176.4 ± 67.50 | 154.3 ± 55.81 |
| AST/SGOT, U/L | 34.8 ± 15.17 | 34.8 ± 12.29 | 32.1 ± 15.14 | 31.4 ± 11.22 | 37.5 ± 14.78 | 37.6 ± 12.62 |
| Calcium, mg/dL | 9.5 ± 0.37* | 9.4 ± 0.31* | 9.4 ± 0.38 | 9.4 ± 0.28 | 9.5 ± 0.35* | 9.3 ± 0.34* |
| Creatinine, mg/dL | 0.5 ± 0.16 | 0.5 ± 0.13 | 0.5 ± 0.15 | 0.5 ± 0.11 | 0.5 ± 0.18 | 0.5 ± 0.15 |
| BUN, mg/dL | 7.5 ± 2.67 | 7.0 ± 2.07 | 7.2 ± 2.16 | 6.7 ± 2.26 | 7.9 ± 3.08 | 7.1 ± 1.93 |
| Vitamin D, ng/mL | 25.0 ± 11.13 | 22.5 ± 8.35 | 24.8 ± 10.85* | 19.6 ± 8.17* | 25.3 ± 11.46 | 25.2 ± 7.70 |
Data are presented as mean ± standard deviation.
ALP, alkaline phosphatase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; LDH, lactate dehydrogenase; SGOT, serum glutamic-oxaloacetic transaminase; WBC, white blood cell count.
P < .05 for normal vs low BMD values, per variable.