Table 1.

Trial characteristics

TrialNPhasePeriod of accrualTreatment induction*Population
CALGB 10201 506 2003-2006 7 + 3 ± oblimersen Older AML 
CALGB 10503 546 2007-2011 7 + 3 + 3  Younger AML 
CALGB 10603 717 2008-2015 7 + 3 ± midostaurin Younger FLT3-mutated AML 
CALGB 10801 61 2011-2014 7 + 3 + dasatinib CBF AML 
CALGB 11001 54 2011-2014 7 + 3 + sorafenib Older FLT3-mutated AML 
TrialNPhasePeriod of accrualTreatment induction*Population
CALGB 10201 506 2003-2006 7 + 3 ± oblimersen Older AML 
CALGB 10503 546 2007-2011 7 + 3 + 3  Younger AML 
CALGB 10603 717 2008-2015 7 + 3 ± midostaurin Younger FLT3-mutated AML 
CALGB 10801 61 2011-2014 7 + 3 + dasatinib CBF AML 
CALGB 11001 54 2011-2014 7 + 3 + sorafenib Older FLT3-mutated AML 

CBF, core binding factor.

*

7 + 3, anthracycline or cytarabine on days 1-7 and daunorubicin on days 1-3; 7 + 3 + 3, anthracycline or cytarabine on days 1-7, daunorubicin on days 1-3, and etoposide on days 1-3.

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