Table 1. Characteristics of CUX1 MT ,... | American Society of Hematology

Table 1.

Characteristics of CUX1^MT, CUX1^DEL, and CUX1^WTcases

	CUX1^MT	CUX1^DEL	CUX1^WT
No.	50	87	1344
Sex, male	50	55	59
Diagnosis, n (%)
MDSs
Low-risk	12/50 (24)	13/87 (15)	335 (25)
High-risk	14/50 (28)	27/87 (31)†	208 (15)
AML
Primary	6/50 (12)	12/87 (14)	304 (23)
Secondary	2/50 (4)	24/87 (28)**†	179 (13)
MDS/MPN	13/50 (26)*	8/87 (9)	196 (15)
MPN	3/50 (6)	3/87 (3)	122 (9)
Cytogenetics, n (%)
Normal	25 (50)	0	509 (38)
Complex	4 (8)	19 (21)‡	147 (11)
Del (5q)	4 (8)	18 (21)‡§	96 (7)
Del (7q/−7)	5 (10)	81 (100)	0
Del (20q)	0	7 (8)	54 (4)
(+8)	3 (6)	3 (3)	81 (6)
−Y	1 (2)	2 (2)	27 (2)
Median blood counts
ANC, ×10⁹/L	10	4	6
Hb, g/dL	10	9	11
Platelets, ×10⁹/L	125	76	133
PB blast, %	9	12	8
BM blast, %	15	20	14

	CUX1^MT	CUX1^DEL	CUX1^WT
No.	50	87	1344
Sex, male	50	55	59
Diagnosis, n (%)
MDSs
Low-risk	12/50 (24)	13/87 (15)	335 (25)
High-risk	14/50 (28)	27/87 (31)†	208 (15)
AML
Primary	6/50 (12)	12/87 (14)	304 (23)
Secondary	2/50 (4)	24/87 (28)**†	179 (13)
MDS/MPN	13/50 (26)*	8/87 (9)	196 (15)
MPN	3/50 (6)	3/87 (3)	122 (9)
Cytogenetics, n (%)
Normal	25 (50)	0	509 (38)
Complex	4 (8)	19 (21)‡	147 (11)
Del (5q)	4 (8)	18 (21)‡§	96 (7)
Del (7q/−7)	5 (10)	81 (100)	0
Del (20q)	0	7 (8)	54 (4)
(+8)	3 (6)	3 (3)	81 (6)
−Y	1 (2)	2 (2)	27 (2)
Median blood counts
ANC, ×10⁹/L	10	4	6
Hb, g/dL	10	9	11
Platelets, ×10⁹/L	125	76	133
PB blast, %	9	12	8
BM blast, %	15	20	14

ANC, absolute neutrophil count; Hb, hemoglobin.

P < .05, **P < .01 compare CUX1^MT vs CUX1^DEL, †P < .01 compares CUX1^DEL vs CUX1^WT, ‡P < .05, §P < .001 compare CUX1^MT vs CUX1^DEL vs CUX1^WT.

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