Antigenic targets in acute myeloid leukemia (AML) that have been used clinically.
| Antigen . | Distribution on Normal and Neoplastic Cells . |
|---|---|
| Abbreviations: ALL, acute lymphocytic leukemia. | |
| CD33 | Myeloid progenitors, monocytes, dendritic cells; most AMLs. Not earliest hematopoietic stem cells. |
| CD45 | Most myeloid and lymphoid cells of various stages of maturation. Most AMLs and ALLs. |
| CD66 | Normal and activated myeloid cells. Not AML blasts; some ALL. |
| CD15 | Le-X antigen. Normal and malignant myeloid and monocytic cells; epithelial cells and carcinomas. |
| CD13 | Broad myeloid and monocytic expression; epithelial and stromal cells and carcinomas. |
| Antigen . | Distribution on Normal and Neoplastic Cells . |
|---|---|
| Abbreviations: ALL, acute lymphocytic leukemia. | |
| CD33 | Myeloid progenitors, monocytes, dendritic cells; most AMLs. Not earliest hematopoietic stem cells. |
| CD45 | Most myeloid and lymphoid cells of various stages of maturation. Most AMLs and ALLs. |
| CD66 | Normal and activated myeloid cells. Not AML blasts; some ALL. |
| CD15 | Le-X antigen. Normal and malignant myeloid and monocytic cells; epithelial cells and carcinomas. |
| CD13 | Broad myeloid and monocytic expression; epithelial and stromal cells and carcinomas. |