Table 8.

Presenting features and physical findings at diagnosis in 215 patients with Waldenstrom’s macroglobulinemia (reprinted from Merlini39 ).

Frequency (%)
Symptoms 
    Weakness 66 
    Anorexia 25 
    Peripheral neuropathy 24 
    Weight loss 17 
    Fever 15 
    Raynaud’s phenomenon 11 
Physical findings 
    Hepatomegaly (> 2 cm from
 the costal margin) 20 
    Splenomegaly 19 
    Lymphadenopathy 15 
    Purpura 
    Hemorrhagic manifestations 
Frequency (%)
Symptoms 
    Weakness 66 
    Anorexia 25 
    Peripheral neuropathy 24 
    Weight loss 17 
    Fever 15 
    Raynaud’s phenomenon 11 
Physical findings 
    Hepatomegaly (> 2 cm from
 the costal margin) 20 
    Splenomegaly 19 
    Lymphadenopathy 15 
    Purpura 
    Hemorrhagic manifestations 
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