Genotype and phenotype of embryos derived from AML1/EVI1 chimeric males mated with normal females
. | . | Genotype . | . | Phenotype of KI*mice . | . | ||
|---|---|---|---|---|---|---|---|
| Stages . | No. of Pups . | +/+ . | +/KI* . | Hemorrhage . | Death . | ||
| E10.5 | 9 | 1 | 8 | 0 | 0 | ||
| E11.5 | 14 | 11 | 3 | 0 | 0 | ||
| E12.5 | 98 | 67 | 31 | 27 | 3 | ||
| E13.5 | 78 | 62 | 16 | 16 | 10 | ||
| E14.5 | 32 | 21 | 11 | 11 | 11 | ||
. | . | Genotype . | . | Phenotype of KI*mice . | . | ||
|---|---|---|---|---|---|---|---|
| Stages . | No. of Pups . | +/+ . | +/KI* . | Hemorrhage . | Death . | ||
| E10.5 | 9 | 1 | 8 | 0 | 0 | ||
| E11.5 | 14 | 11 | 3 | 0 | 0 | ||
| E12.5 | 98 | 67 | 31 | 27 | 3 | ||
| E13.5 | 78 | 62 | 16 | 16 | 10 | ||
| E14.5 | 32 | 21 | 11 | 11 | 11 | ||
Genotype analysis was performed by Southern analysis of DNA extracted from embryos. Surviving embryos were defined as those with beating hearts at the time of dissection.
KI indicates AML1/EVI1 knock-in.