Hematopoietic progenitors in E12.5 and E13.5 fetal liver
Stages/genotype . | No. of Pups . | BFU-E . | CFU-GM . | CFU-GEMM . | CFU-M . |
|---|---|---|---|---|---|
| E12.5 | |||||
| +/+ | 13 | 10 ± 3 | 32 ± 8 | 20 ± 9 | 8 ± 2 |
| AML1/EVI1/+ | 6 | 0 | 0 | 0 | 25 ± 11 |
| E13.5 | |||||
| +/+ | 9 | 8 ± 3 | 58 ± 14 | 25 ± 11 | 10 ± 3 |
| AML1/EVI1/+ | 5 | 0 | 0 | 154 ± 54 | 4 ± 3 |
Stages/genotype . | No. of Pups . | BFU-E . | CFU-GM . | CFU-GEMM . | CFU-M . |
|---|---|---|---|---|---|
| E12.5 | |||||
| +/+ | 13 | 10 ± 3 | 32 ± 8 | 20 ± 9 | 8 ± 2 |
| AML1/EVI1/+ | 6 | 0 | 0 | 0 | 25 ± 11 |
| E13.5 | |||||
| +/+ | 9 | 8 ± 3 | 58 ± 14 | 25 ± 11 | 10 ± 3 |
| AML1/EVI1/+ | 5 | 0 | 0 | 154 ± 54 | 4 ± 3 |
Numbers represent colonies per 1 × 104 fetal liver cells, mean ± SD.
BFU-E indicates erythroid burst-forming unit; CFU-GM, granulocyte/macrophage colony-forming unit; CFU-GEMM, granulocyte/erythrocyte/macrophage/megakaryocyte colony-forming unit; CFU-M, macrophage colony-forming unit.