Multivariate analysis of overall survival
. | All ages, adjusted for age and sex . | Young adults, adjusted for sex . | Older adults, adjusted for sex . |
|---|---|---|---|
| EBV status, adjusted for stage and B symptoms | 1.45 (1.00−2.11) | 0.60 (0.20−1.76) | 1.88 (1.14−3.12)* |
| EBV status, adjusted for early versus advanced stage disease | 1.39 (0.97−2.01) | 0.55 (0.19−1.62) | 1.96 (1.19−3.22)* |
| B symptoms, adjusted for EBV and stage | 1.49 (1.01−2.19)* | 1.70 (0.77−3.74) | 1.49 (0.90−2.47) |
| Early/advanced, adjusted for EBV | 2.05 (1.38−3.06)* | 2.87 (1.17−7.06)* | 1.62 (0.96−2.75) |
| Stage, adjusted for EBV status and B symptoms | 1.44 (1.19−1.73)* | 1.55 (1.02−2.38)* | 1.29 (1.01−1.66)* |
. | All ages, adjusted for age and sex . | Young adults, adjusted for sex . | Older adults, adjusted for sex . |
|---|---|---|---|
| EBV status, adjusted for stage and B symptoms | 1.45 (1.00−2.11) | 0.60 (0.20−1.76) | 1.88 (1.14−3.12)* |
| EBV status, adjusted for early versus advanced stage disease | 1.39 (0.97−2.01) | 0.55 (0.19−1.62) | 1.96 (1.19−3.22)* |
| B symptoms, adjusted for EBV and stage | 1.49 (1.01−2.19)* | 1.70 (0.77−3.74) | 1.49 (0.90−2.47) |
| Early/advanced, adjusted for EBV | 2.05 (1.38−3.06)* | 2.87 (1.17−7.06)* | 1.62 (0.96−2.75) |
| Stage, adjusted for EBV status and B symptoms | 1.44 (1.19−1.73)* | 1.55 (1.02−2.38)* | 1.29 (1.01−1.66)* |
Data are presented as risk ratio (95% confidence interval).
Risk ratios (RRs) are for EBV-positive relative to EBV-negative cases, presence or absence of B symptoms, and advanced-stage relative to early-stage disease; stage has been modeled as a trend across all stages and RRs are an estimate of increased risk for each increase in stage (eg, stage III relative to stage II disease).
RR indicates risk ratio; CI, confidence interval; and EBV, Epstein-Barr virus.
Significant values.