Association between EBV status and previous shingles, prior malignancy, and depcat score
. | All cases, no. (%) . | EBV negative, no. (%) . | EBV positive, no. (%) . | P* . |
|---|---|---|---|---|
| All ages | ||||
| Shingles | .01‡ | |||
| Yes | 26 (8.3) | 12 (5.6) | 14 (14) | |
| No | 289 (91.7) | 203 (94.4) | 86 (86) | |
| Prior cancer | .21 | |||
| Yes | 12 (2.7) | 6 (2.1) | 6 (4.1) | |
| No | 425 (97.3) | 28 (97.9) | 139 (95.9) | |
| Depcat§ | .33 | |||
| 1 | 47 (15.1) | 34 (16.1) | 13 (12.9) | |
| 2 | 52 (16.7) | 38 (18.0) | 14 (13.9) | |
| 3 | 58 (18.6) | 39 (8.5) | 19 (18.8) | |
| 4 | 71 (22.8) | 41 (19.4) | 30 (29.7) | |
| 5 | 84 (26.9) | 59 (28.0) | 25 (24.8) | |
| Young adults, 15 to 34 years | ||||
| Shingles† | .20 | |||
| Yes | 13 (7.4) | 8 (6.0) | 5 (11.9) | |
| No | 162 (92.6) | 125 (94.0) | 37 (88.1) | |
| Prior cancer | .20 | |||
| Yes | 4 (1.8) | 2 (1.1) | 2 (3.8) | |
| No | 223 (98.2) | 172 (98.9) | 51 (96.2) | |
| Depcat§ | .56 | |||
| 1 | 24 (14.0) | 18 (13.7) | 6 (15.0) | |
| 2 | 29 (17.0) | 24 (18.3) | 5 (12.5) | |
| 3 | 37 (21.6) | 29 (22.1) | 8 (20.0) | |
| 4 | 36 (21.1) | 24 (18.3) | 12 (30.0) | |
| 5 | 45 (26.3) | 36 (27.5) | 9 (22.5) | |
| Older adults, 50 y or older | ||||
| Shinglest† | .27 | |||
| Yes | 9 (11.4) | 3 (7.5) | 6 (15.4) | |
| No | 70 (88.6) | 37 (92.5) | 33 (84.6) | |
| Prior cancer | .713 | |||
| Yes | 7 (5.5) | 3 (4.8) | 4 (6.3) | |
| No | 120 (94.5) | 60 (95.2) | 60 (93.8) | |
| Depcat§ | .04‡ | |||
| 1 | 13 (15.9) | 9 (22.0) | 4 (9.8) | |
| 2 | 13 (15.9) | 7 (17.1) | 6 (14.6) | |
| 3 | 9 (11.0) | 3 (7.3) | 6 (14.6) | |
| 4 | 20 (24.4) | 5 (12.2) | 15 (36.6) | |
| 5 | 27 (32.9) | 17 (41.5) | 10 (24.4) |
. | All cases, no. (%) . | EBV negative, no. (%) . | EBV positive, no. (%) . | P* . |
|---|---|---|---|---|
| All ages | ||||
| Shingles | .01‡ | |||
| Yes | 26 (8.3) | 12 (5.6) | 14 (14) | |
| No | 289 (91.7) | 203 (94.4) | 86 (86) | |
| Prior cancer | .21 | |||
| Yes | 12 (2.7) | 6 (2.1) | 6 (4.1) | |
| No | 425 (97.3) | 28 (97.9) | 139 (95.9) | |
| Depcat§ | .33 | |||
| 1 | 47 (15.1) | 34 (16.1) | 13 (12.9) | |
| 2 | 52 (16.7) | 38 (18.0) | 14 (13.9) | |
| 3 | 58 (18.6) | 39 (8.5) | 19 (18.8) | |
| 4 | 71 (22.8) | 41 (19.4) | 30 (29.7) | |
| 5 | 84 (26.9) | 59 (28.0) | 25 (24.8) | |
| Young adults, 15 to 34 years | ||||
| Shingles† | .20 | |||
| Yes | 13 (7.4) | 8 (6.0) | 5 (11.9) | |
| No | 162 (92.6) | 125 (94.0) | 37 (88.1) | |
| Prior cancer | .20 | |||
| Yes | 4 (1.8) | 2 (1.1) | 2 (3.8) | |
| No | 223 (98.2) | 172 (98.9) | 51 (96.2) | |
| Depcat§ | .56 | |||
| 1 | 24 (14.0) | 18 (13.7) | 6 (15.0) | |
| 2 | 29 (17.0) | 24 (18.3) | 5 (12.5) | |
| 3 | 37 (21.6) | 29 (22.1) | 8 (20.0) | |
| 4 | 36 (21.1) | 24 (18.3) | 12 (30.0) | |
| 5 | 45 (26.3) | 36 (27.5) | 9 (22.5) | |
| Older adults, 50 y or older | ||||
| Shinglest† | .27 | |||
| Yes | 9 (11.4) | 3 (7.5) | 6 (15.4) | |
| No | 70 (88.6) | 37 (92.5) | 33 (84.6) | |
| Prior cancer | .713 | |||
| Yes | 7 (5.5) | 3 (4.8) | 4 (6.3) | |
| No | 120 (94.5) | 60 (95.2) | 60 (93.8) | |
| Depcat§ | .04‡ | |||
| 1 | 13 (15.9) | 9 (22.0) | 4 (9.8) | |
| 2 | 13 (15.9) | 7 (17.1) | 6 (14.6) | |
| 3 | 9 (11.0) | 3 (7.3) | 6 (14.6) | |
| 4 | 20 (24.4) | 5 (12.2) | 15 (36.6) | |
| 5 | 27 (32.9) | 17 (41.5) | 10 (24.4) |
EBV indicates Epstein Barr virus.
P value for chi-squared analysis.
Shingles (herpes zoster reactivation) diagnosed more than 1 year before diagnosis of Hodgkin lymphoma.
Significant values.
Depcat score using the Carstairs index analyzed as a trend across depcat categories; Carstairs categories 1 and 2 (most affluent) are grouped as depcat 1, and Carstairs categories 6 and 7 are grouped as depcat 5 (least affluent).