Mean values for laboratory tests at baseline and at weeks 6, 16, and 60
Measure . | Baseline . | Week 6 . | Week 16 . | Week 60* . |
|---|---|---|---|---|
| Fibrinogen level, mg/dL | 639 ± 36 | 357 ± 28† | 317 ± 28† | 317 ± 22† |
| ESR, mm/h | 114 ± 7 | 63 ± 7† | 48 ± 8† | 40 ± 7† |
| HDL cholesterol level, mg/dL | 36.1 ± 2.4 | 52.0 ± 4.6† | 52.7 ± 5.3† | 49.4 ± 3.0† |
| LDL cholesterol level, mg/dL | 71.4 ± 4.6 | 96.8 ± 5.4† | 106.5 ± 4.9† | 109.5 ± 5.9† |
| Triglyceride level, mg/dL | 54 ± 4 | 105 ± 11† | 121 ± 15† | 138 ± 19† |
| Body weight, kg | 56.3 ± 2.0 | 58.1 ± 2.0 | 60.1 ± 2.2 | 61.0 ± 2.3 |
| BMI | 21.6 ± 0.6 | 22.3 ± 0.6† | 23.1 ± 0.6† | 23.4 ± 0.6† |
| General fatigue, mm | 29.9 ± 4.3 | 17.4 ± 3.3‡ | 17.7 ± 3.2§ | 20.4 ± 3.8 |
| IgA, g/L | 3.19 ± 0.31 | 2.58 ± 0.28† | 2.47 ± 0.29† | 2.26 ± 0.21† |
| IgM, g/L | 7.13 ± 0.73 | 3.82 ± 0.38† | 3.44 ± 0.38† | 3.30 ± 0.33† |
| IgE, mg/L | 5.03 ± 1.05 | 3.49 ± 0.85† | 4.64 ± 1.62 | 3.99 ± 0.92† |
| Neutrophil count, × 109/L | 5.2 ± 0.7 | 4.5 ± 0.5† | 4.3 ± 0.6† | 4.3 ± 0.4† |
Measure . | Baseline . | Week 6 . | Week 16 . | Week 60* . |
|---|---|---|---|---|
| Fibrinogen level, mg/dL | 639 ± 36 | 357 ± 28† | 317 ± 28† | 317 ± 22† |
| ESR, mm/h | 114 ± 7 | 63 ± 7† | 48 ± 8† | 40 ± 7† |
| HDL cholesterol level, mg/dL | 36.1 ± 2.4 | 52.0 ± 4.6† | 52.7 ± 5.3† | 49.4 ± 3.0† |
| LDL cholesterol level, mg/dL | 71.4 ± 4.6 | 96.8 ± 5.4† | 106.5 ± 4.9† | 109.5 ± 5.9† |
| Triglyceride level, mg/dL | 54 ± 4 | 105 ± 11† | 121 ± 15† | 138 ± 19† |
| Body weight, kg | 56.3 ± 2.0 | 58.1 ± 2.0 | 60.1 ± 2.2 | 61.0 ± 2.3 |
| BMI | 21.6 ± 0.6 | 22.3 ± 0.6† | 23.1 ± 0.6† | 23.4 ± 0.6† |
| General fatigue, mm | 29.9 ± 4.3 | 17.4 ± 3.3‡ | 17.7 ± 3.2§ | 20.4 ± 3.8 |
| IgA, g/L | 3.19 ± 0.31 | 2.58 ± 0.28† | 2.47 ± 0.29† | 2.26 ± 0.21† |
| IgM, g/L | 7.13 ± 0.73 | 3.82 ± 0.38† | 3.44 ± 0.38† | 3.30 ± 0.33† |
| IgE, mg/L | 5.03 ± 1.05 | 3.49 ± 0.85† | 4.64 ± 1.62 | 3.99 ± 0.92† |
| Neutrophil count, × 109/L | 5.2 ± 0.7 | 4.5 ± 0.5† | 4.3 ± 0.6† | 4.3 ± 0.4† |
Values are expressed as mean ± standard error. To convert fibrinogen from milligrams per deciliter to micromoles per liter, multiply milligrams per deciliter by 0.0249. To convert HDL and LDL cholesterol from milligrams per deciliter to millimoles per liter, multiply milligrams per deciliter by 0.02586. To convert triglyceride from milligrams per deciliter to millimoles per liter, multiply milligrams per deciliter by 0.0113.
ESR indicates erythrocyte sedimentation rate; LDL, low-density lipoprotein; BMI, body mass index.
Patients treated with MRA up to 16 weeks (n = 28) and up to 60 weeks (n = 27).
P < .001; paired t test compared with baseline.
P = .01; paired t test compared with baseline.
P = .008; paired t test compared with baseline.