Table 2. VB-JB restriction of... | American Society of Hematology

Table 2.

VB-JB restriction of immunodominant clones in studied patients

Patient no.	VB	% VB family expansion	JB
1	14	90	JB2.1
2	3	88	JB2.4
3	22	89	JB2.7
4	17	83	JB2.3
5	9	64	JB1.1
6	8	26	JB1.5
7	6	NA	JB2.1
8	23	15	JB1.1, JB2.7*
8	14	16	JB2.7
9	3	63	JB1.1
10	7	76	JB2.7
11	20	23	JB2.1, JB2.7*
12	14	65	JB2.7
13	12	24	JB2.6
14	2	40	JB2.7
15	18	8	JB1.1, JB2.3*
16	2	90	JB2.7
17	2	20	JB2.1
17	21	31	JB2.1
18	17	45	JB2.3
18	3	25	JB2.1
19	2	38	JB2.3
20	14	22	JB1.2
21	13	7	JB1.6
22	3	26	JB1.5
23	3	33	JB2.7
24	2	80	JB2.7
25	15	NA	JB2.1, JB2.3*
26	9	25	JB2.5
27	13	43	JB1.1
27	18	25	JB2.7
27	22	NA	JB2.7
28	13	65	JB2.7
29	5.3	25	JB2.7
30	15	NA	JB1.2, JB2.3*
31	5	NA	JB1.2
32	15	NA	JB2.5, JB2.1, JB2.5*
33	18	27	JB2.7
34	3	10	JB2.7
34	22	60	JB1.2
35	7	NA	JB1.6
36	9	78	JB2.4
37	13	80	JB2.5
38	12	93	JB2.1
39	7	46	JB2.2
40	24	NA	JB2.2
40	13	NA	JB1.2
41	15	NA	JB2.7
41	24	NA	JB2.5
42	6	NA	JB2.5
42	15	NA	JB2.4
43	6	NA	JB2.3
43	24	NA	JB2.1
43	12	NA	JB2.3
44	9	81	JB2.3
44	21	11	JB1.1
45	24	NA	JB1.1
46	6	NA	JB2.1, JB2.7*
46	17	8	JB2.1
47	6	NA	JB2.7
47	24	NA	JB2.3
48	13	93	JB1.1
49	1	70	JB1.5
50	13	6	JB2.7
51	12	8	JB2.1
51	6	NA	JB1.1
52	1	NA	JB1.1
53	18	42	JB2.7
54	13	6	JB2.7, JB2.5*
55	13	7	JB2.3
55	18	78	JB2.5
56	4	22	JB2.1
57	13	89	JB2.5
58	3	NA	JB2.7
58	13	NA	JB1.5
59	1	95	JB1.6
60	14	28	JB2.1

Patient no.	VB	% VB family expansion	JB
1	14	90	JB2.1
2	3	88	JB2.4
3	22	89	JB2.7
4	17	83	JB2.3
5	9	64	JB1.1
6	8	26	JB1.5
7	6	NA	JB2.1
8	23	15	JB1.1, JB2.7*
8	14	16	JB2.7
9	3	63	JB1.1
10	7	76	JB2.7
11	20	23	JB2.1, JB2.7*
12	14	65	JB2.7
13	12	24	JB2.6
14	2	40	JB2.7
15	18	8	JB1.1, JB2.3*
16	2	90	JB2.7
17	2	20	JB2.1
17	21	31	JB2.1
18	17	45	JB2.3
18	3	25	JB2.1
19	2	38	JB2.3
20	14	22	JB1.2
21	13	7	JB1.6
22	3	26	JB1.5
23	3	33	JB2.7
24	2	80	JB2.7
25	15	NA	JB2.1, JB2.3*
26	9	25	JB2.5
27	13	43	JB1.1
27	18	25	JB2.7
27	22	NA	JB2.7
28	13	65	JB2.7
29	5.3	25	JB2.7
30	15	NA	JB1.2, JB2.3*
31	5	NA	JB1.2
32	15	NA	JB2.5, JB2.1, JB2.5*
33	18	27	JB2.7
34	3	10	JB2.7
34	22	60	JB1.2
35	7	NA	JB1.6
36	9	78	JB2.4
37	13	80	JB2.5
38	12	93	JB2.1
39	7	46	JB2.2
40	24	NA	JB2.2
40	13	NA	JB1.2
41	15	NA	JB2.7
41	24	NA	JB2.5
42	6	NA	JB2.5
42	15	NA	JB2.4
43	6	NA	JB2.3
43	24	NA	JB2.1
43	12	NA	JB2.3
44	9	81	JB2.3
44	21	11	JB1.1
45	24	NA	JB1.1
46	6	NA	JB2.1, JB2.7*
46	17	8	JB2.1
47	6	NA	JB2.7
47	24	NA	JB2.3
48	13	93	JB1.1
49	1	70	JB1.5
50	13	6	JB2.7
51	12	8	JB2.1
51	6	NA	JB1.1
52	1	NA	JB1.1
53	18	42	JB2.7
54	13	6	JB2.7, JB2.5*
55	13	7	JB2.3
55	18	78	JB2.5
56	4	22	JB2.1
57	13	89	JB2.5
58	3	NA	JB2.7
58	13	NA	JB1.5
59	1	95	JB1.6
60	14	28	JB2.1

VB indicates variable beta chain (VB family) of the TCR; JB, joining beta chain of the expanded clonotypes; NA, not available.

Cases in which 2 (3 in patient 32) immunodominant clonotypes with identical VB but different JB families were detected.