Laboratory characteristics of patients and healthy volunteers who provided urine samples for the clinical validation
. | Hemoglobin, mM . | MCV, fL . | Serum iron (Fe), μM . | Fe/TIBC (TS), % . | Ferritin, μg/L . | CRP, mg/L . |
|---|---|---|---|---|---|---|
| Normal, n = 7 | 8.1 (7.8–9.1) | NA | 20 (14–29) | 32.8 (24.6–52.7) | 80 (32–190) | < 5 (< 5–8) |
| Secondary iron overload, n = 8 | 5.6 (3.4–6.2) | NA | 39 (29–63) | 96.0 (77.1–100.0) | 3088 (568–14 496) | < 5 (< 5–< 5) |
| Hereditary hemochromatosis, n = 7 | 8.7 (7.2–9.6) | NA | 27 (9–39) | 50.9 (16.1–93.5) | 54 (12–2118) | <5 (< 5–< 5) |
| Iron deficiency anemia, n = 6 | 7.1 (3.3–7.4) | 78 (69–84) | 10 (2–11) | 16.0 (2.4–19.6) | 8 (2–11) | < 5 (< 5–6) |
| Endotoxemia model, n = 6 | 8.1 (7.2–9.1) | NA | 16 (4–22) | 25.6 (8.0–38.6) | 65 (15–219) | 8 (5–33) |
| Sepsis, n = 4 | 5.4 (4.9–6.2) | NA | 1 (1–4) | 7.1 (3.8–17.4) | 370 (280–505) | 192 (124–227) |
. | Hemoglobin, mM . | MCV, fL . | Serum iron (Fe), μM . | Fe/TIBC (TS), % . | Ferritin, μg/L . | CRP, mg/L . |
|---|---|---|---|---|---|---|
| Normal, n = 7 | 8.1 (7.8–9.1) | NA | 20 (14–29) | 32.8 (24.6–52.7) | 80 (32–190) | < 5 (< 5–8) |
| Secondary iron overload, n = 8 | 5.6 (3.4–6.2) | NA | 39 (29–63) | 96.0 (77.1–100.0) | 3088 (568–14 496) | < 5 (< 5–< 5) |
| Hereditary hemochromatosis, n = 7 | 8.7 (7.2–9.6) | NA | 27 (9–39) | 50.9 (16.1–93.5) | 54 (12–2118) | <5 (< 5–< 5) |
| Iron deficiency anemia, n = 6 | 7.1 (3.3–7.4) | 78 (69–84) | 10 (2–11) | 16.0 (2.4–19.6) | 8 (2–11) | < 5 (< 5–6) |
| Endotoxemia model, n = 6 | 8.1 (7.2–9.1) | NA | 16 (4–22) | 25.6 (8.0–38.6) | 65 (15–219) | 8 (5–33) |
| Sepsis, n = 4 | 5.4 (4.9–6.2) | NA | 1 (1–4) | 7.1 (3.8–17.4) | 370 (280–505) | 192 (124–227) |
Data are expressed as the median with the range in parentheses.
NA indicates not analyzed; CRP, C-reactive protein; and TIBC, total iron binding capacity.