HM1.24-derived peptides and their predictive binding scores
. | . | HLA-A2 binding score . | . | HLA-A24 binding score . | . | ||
|---|---|---|---|---|---|---|---|
| Antigen position . | Sequence . | BIMAS . | SYFPEITHI . | BIMAS . | SYFPEITHI . | ||
| HM1.24 | |||||||
| 126-134 | KLQDASAEV | 998.1 | 26 | 0.4 | 2 | ||
| 136-144 | RLRRENQVL | 0.7 | 20 | 9.6 | 9 | ||
| 152-160 | KYYPSSQDS | 0.0 | 4 | 14.4 | 12 | ||
| 165-173 | APQLLIVLL | 0.3 | 19 | 7.2 | 13 | ||
| MAGE-3 | |||||||
| 195-203 | IMPKAGLLI | 12.8 | 19 | 1.5 | 15 | ||
. | . | HLA-A2 binding score . | . | HLA-A24 binding score . | . | ||
|---|---|---|---|---|---|---|---|
| Antigen position . | Sequence . | BIMAS . | SYFPEITHI . | BIMAS . | SYFPEITHI . | ||
| HM1.24 | |||||||
| 126-134 | KLQDASAEV | 998.1 | 26 | 0.4 | 2 | ||
| 136-144 | RLRRENQVL | 0.7 | 20 | 9.6 | 9 | ||
| 152-160 | KYYPSSQDS | 0.0 | 4 | 14.4 | 12 | ||
| 165-173 | APQLLIVLL | 0.3 | 19 | 7.2 | 13 | ||
| MAGE-3 | |||||||
| 195-203 | IMPKAGLLI | 12.8 | 19 | 1.5 | 15 | ||
HLA-binding peptides in HM1.24 protein were identified using 2 computer algorithms (BIMAS and SYFPEITHI). The binding scores represent an estimated half-time of dissociation or binding capacity of each peptide to HLA-A*0201 or HLA-A*2402 molecules.