Table 1. Lymphoma Characterization in... | American Society of Hematology

Table 1.

Lymphoma Characterization in MSH2^−/− Mice

Mouse	Histology	Immunophenotype	TdT	TCR Status β/δ	RBTN-2	Tal-1
D8	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	+ve
L12	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	+ve
R15	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	−ve
H27	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	−/+	+ve	−ve
K7	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	−/+	+ve	−ve
P21	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	+ve
T9	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	+ve
L15	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
F3	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
B20	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
S7	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	−/+	+ve	−ve
C31	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	−/+	+ve	+ve
F1-C2	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	+ve
E5	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
H59	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
E38	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
J3	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	−/+	+ve	+ve
E22	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	+/+	+ve	−ve
K1	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	+/+	+ve	−ve
F1-C3	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	−/+	+ve	+ve

Mouse	Histology	Immunophenotype	TdT	TCR Status β/δ	RBTN-2	Tal-1
D8	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	+ve
L12	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	+ve
R15	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	+/+	+ve	−ve
H27	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	−/+	+ve	−ve
K7	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁻	+ve	−/+	+ve	−ve
P21	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	+ve
T9	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	+ve
L15	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
F3	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
B20	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	+/+	+ve	−ve
S7	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	−/+	+ve	−ve
C31	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁺	+ve	−/+	+ve	+ve
F1-C2	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	+ve
E5	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
H59	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
E38	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	+/+	+ve	−ve
J3	Lymphoblastic	B220⁻, CD3⁺, CD4⁺, CD8⁻	+ve	−/+	+ve	+ve
E22	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	+/+	+ve	−ve
K1	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	+/+	+ve	−ve
F1-C3	Lymphoblastic	B220⁻, CD3⁺, CD4⁻, CD8⁺	+ve	−/+	+ve	+ve

TdT refers to terminal deoxynucleotidyl transferase activity. TCR status refers to the T-cell receptor β and δ genes, and the (+) and (−) refers to the presence or absence of T-cell receptor gene rearrangements. For TCR δ the (+) includes both rearrangements and deletions.

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