Clinical and Laboratory Data at the Time of Study
| . | No 11q Deletion (N = 171) . | 11q Deletion (N = 43) . | P Value . |
|---|---|---|---|
| Median age (yr) | 63 (37-84) | 58 (36-85) | .01† |
| Male sex | 104 (61%) | 27 (63%) | .86‡ |
| Stage at study | .01ρ | ||
| Rai 0 | 24 (14.0%) | 1 (2.3%) | |
| Rai 1 | 17 (9.9%) | 4 (9.3%) | |
| Rai 2 | 86 (50.3%) | 19 (44.2%) | |
| Rai 3 | 18 (10.5%) | 9 (20.9%) | |
| Rai 4 | 26 (15.2%) | 10 (23.3%) | |
| B symptoms (%) | 37 (21.6%) | 16 (37.2%) | .04‡ |
| White blood cell count (×109/L) | 35.8 | 55.4 | .35† |
| Hemoglobin (g/dL) | 13.1 | 11.7 | .03† |
| Platelet count (×109/L) | 166 | 154 | .20† |
| Lactate dehydrogenase (IU/L) | 174 | 197 | .07† |
| Alkaline phosphatase (IU/L) | 128 | 133 | .30† |
| Albumin (g/L) | 45 | 45 | .58† |
| IgG (g/L) | 9.39 | 8.77 | .42† |
| IgA (g/L) | 1.28 | 0.85 | .04† |
| IgM (g/L) | 0.60 | 0.73 | .60† |
| Splenomegaly (%) | 122 (71.3%) | 35 (81.4%) | .32‡ |
| Peripheral lymphadenopathy (cm2 )* | 4 | 17 | <.001† |
| Mediastinal lymphadenopathy (%) | 5.3 | 23.3 | <.001‡ |
| Abdominal lymphadenopathy (%) | 48.0 | 88.4 | <.001‡ |
| Largest lymph node diameter (cm) | 2.0 | 4.3 | <.001† |
| . | No 11q Deletion (N = 171) . | 11q Deletion (N = 43) . | P Value . |
|---|---|---|---|
| Median age (yr) | 63 (37-84) | 58 (36-85) | .01† |
| Male sex | 104 (61%) | 27 (63%) | .86‡ |
| Stage at study | .01ρ | ||
| Rai 0 | 24 (14.0%) | 1 (2.3%) | |
| Rai 1 | 17 (9.9%) | 4 (9.3%) | |
| Rai 2 | 86 (50.3%) | 19 (44.2%) | |
| Rai 3 | 18 (10.5%) | 9 (20.9%) | |
| Rai 4 | 26 (15.2%) | 10 (23.3%) | |
| B symptoms (%) | 37 (21.6%) | 16 (37.2%) | .04‡ |
| White blood cell count (×109/L) | 35.8 | 55.4 | .35† |
| Hemoglobin (g/dL) | 13.1 | 11.7 | .03† |
| Platelet count (×109/L) | 166 | 154 | .20† |
| Lactate dehydrogenase (IU/L) | 174 | 197 | .07† |
| Alkaline phosphatase (IU/L) | 128 | 133 | .30† |
| Albumin (g/L) | 45 | 45 | .58† |
| IgG (g/L) | 9.39 | 8.77 | .42† |
| IgA (g/L) | 1.28 | 0.85 | .04† |
| IgM (g/L) | 0.60 | 0.73 | .60† |
| Splenomegaly (%) | 122 (71.3%) | 35 (81.4%) | .32‡ |
| Peripheral lymphadenopathy (cm2 )* | 4 | 17 | <.001† |
| Mediastinal lymphadenopathy (%) | 5.3 | 23.3 | <.001‡ |
| Abdominal lymphadenopathy (%) | 48.0 | 88.4 | <.001‡ |
| Largest lymph node diameter (cm) | 2.0 | 4.3 | <.001† |