Table 1. Circulating TNF and IL-1α... | American Society of Hematology

Table 1.

Circulating TNF and IL-1α Concentrations 90 Minutes After an LPS Challenge (10 μg/Mouse) in Normal and Neutropenic Mice Treated With Saline (Control Group), Catalase (32,000 U/Mouse, 1 hour Before LPS), or Sodium Bicarbonate (100 mg/kg BID Starting on Day −4)

	TNFα (ng/mL)	IL-1α (pg/mL)
Nonneutropenic
Control	2.1 ± 0.7	78 ± 13
Catalase	0.6 ± 0.6^*	242 ± 105^*
Bicarbonate	1.4 ± 0.9	58 ± 30
Neutropenic
Control	3.5 ± 0.8	114 ± 48
Catalase	0.15 ± 0.1^†	150 ± 59
Bicarbonate	0.7 ± 0.4^*	72 ± 19^*

	TNFα (ng/mL)	IL-1α (pg/mL)
Nonneutropenic
Control	2.1 ± 0.7	78 ± 13
Catalase	0.6 ± 0.6^*	242 ± 105^*
Bicarbonate	1.4 ± 0.9	58 ± 30
Neutropenic
Control	3.5 ± 0.8	114 ± 48
Catalase	0.15 ± 0.1^†	150 ± 59
Bicarbonate	0.7 ± 0.4^*	72 ± 19^*

P < .05 v control.

†

P < .01 v control.

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