Effect of Various Cytokines on the Loss of Leukemic (Ph+) LTC-IC Activity in 10-Day Cultures of CD34+CD38− CML Blood Cells
CML No.* . | Day 0 LTC-IC . | Day 10 LTC-IC (per 100 input cells) . | |||
---|---|---|---|---|---|
. | (per 100 input cells) . | FL . | SF . | IL-3 . | FL, SF, IL-3 . |
1 | 27 | <0.002 | <0.002 | <0.002 | <0.002 |
2 | 2 | <0.002 | <0.002 | <0.002 | <0.002 |
3 | 9 | <0.001 | <0.001 | <0.001 | 0.001 |
4 | 9 | 0.3 | 0.1 | 0.1 | 0.2 |
CML No.* . | Day 0 LTC-IC . | Day 10 LTC-IC (per 100 input cells) . | |||
---|---|---|---|---|---|
. | (per 100 input cells) . | FL . | SF . | IL-3 . | FL, SF, IL-3 . |
1 | 27 | <0.002 | <0.002 | <0.002 | <0.002 |
2 | 2 | <0.002 | <0.002 | <0.002 | <0.002 |
3 | 9 | <0.001 | <0.001 | <0.001 | 0.001 |
4 | 9 | 0.3 | 0.1 | 0.1 | 0.2 |
Same patient samples as in Table 1. The experiments were performed concurrently using the same general culture conditions and cytokine concentrations.