Table 2.

Effect of Various Cytokines on the Loss of Leukemic (Ph+) LTC-IC Activity in 10-Day Cultures of CD34+CD38 CML Blood Cells

CML No.*Day 0 LTC-ICDay 10 LTC-IC (per 100 input cells)
(per 100 input cells)FLSFIL-3FL, SF, IL-3
27 <0.002 <0.002 <0.002 <0.002 
<0.002 <0.002 <0.002 <0.002 
<0.001 <0.001 <0.001 0.001 
0.3 0.1 0.1 0.2 
CML No.*Day 0 LTC-ICDay 10 LTC-IC (per 100 input cells)
(per 100 input cells)FLSFIL-3FL, SF, IL-3
27 <0.002 <0.002 <0.002 <0.002 
<0.002 <0.002 <0.002 <0.002 
<0.001 <0.001 <0.001 0.001 
0.3 0.1 0.1 0.2 
*

Same patient samples as in Table 1. The experiments were performed concurrently using the same general culture conditions and cytokine concentrations.

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