Restoration of Sensitivity to ADM in ATL Cell Lines
| Variable . | IC50 ( μmol/L) . | ||
|---|---|---|---|
| . | Jurkat . | ATL-2 . | ATL-2/ADM cl-2 . |
| Without selenite | 0.12 ± 0.02 | 1.27 ± 0.18 | 3.93 ± 1.15 |
| With selenite | 0.11 ± 0.03 | 0.24 ± 0.034-150 | 1.66 ± 0.224-150 |
| Without diamide | 0.25 ± 0.01 | 1.13 ± 0.04 | 2.90 ± 0.21 |
| With diamide | 0.22 ± 0.01 | 0.44 ± 0.014-150 | 0.81 ± 0.174-150 |
| Variable . | IC50 ( μmol/L) . | ||
|---|---|---|---|
| . | Jurkat . | ATL-2 . | ATL-2/ADM cl-2 . |
| Without selenite | 0.12 ± 0.02 | 1.27 ± 0.18 | 3.93 ± 1.15 |
| With selenite | 0.11 ± 0.03 | 0.24 ± 0.034-150 | 1.66 ± 0.224-150 |
| Without diamide | 0.25 ± 0.01 | 1.13 ± 0.04 | 2.90 ± 0.21 |
| With diamide | 0.22 ± 0.01 | 0.44 ± 0.014-150 | 0.81 ± 0.174-150 |
The mean ± SD of results obtained from 3 different experiments is shown.
P < .01.