Univariable Analysis of Relapse
| Variable . | Relative Risk . | 95% CI . | P Value . |
|---|---|---|---|
| PCR status | |||
| Negative | 1.0 | ||
| p190 or p210+ | 5.7 | 1.2-26.0 | .025 |
| PCR status | |||
| Negative | 1.0 | ||
| p190+ | 11.2 | 2.3-54.8 | .003 |
| Donor type | |||
| Auto, twin, Rel= | 1.0 | ||
| URD, Rel-mm | 0.4 | 0.1-1.4 | .133 |
| Acute GVHD | |||
| Grades 0-1 | 1.0 | ||
| Grades 2-4 | 0.6 | 0.2-2.0 | .427 |
| Phase of disease | |||
| Remission | 1.0 | ||
| Relapse | 2.6 | 0.8-8.3 | .106 |
| Conditioning | |||
| TBI > 1,200 cGY | 1.0 | ||
| Chemo only or <1,200 cGy | 4.6 | 1.5-14.5 | .008 |
| Variable . | Relative Risk . | 95% CI . | P Value . |
|---|---|---|---|
| PCR status | |||
| Negative | 1.0 | ||
| p190 or p210+ | 5.7 | 1.2-26.0 | .025 |
| PCR status | |||
| Negative | 1.0 | ||
| p190+ | 11.2 | 2.3-54.8 | .003 |
| Donor type | |||
| Auto, twin, Rel= | 1.0 | ||
| URD, Rel-mm | 0.4 | 0.1-1.4 | .133 |
| Acute GVHD | |||
| Grades 0-1 | 1.0 | ||
| Grades 2-4 | 0.6 | 0.2-2.0 | .427 |
| Phase of disease | |||
| Remission | 1.0 | ||
| Relapse | 2.6 | 0.8-8.3 | .106 |
| Conditioning | |||
| TBI > 1,200 cGY | 1.0 | ||
| Chemo only or <1,200 cGy | 4.6 | 1.5-14.5 | .008 |
Univariable analysis of the relative risk of relapse associated with PCR status, donor type, acute and chronic GVHD, remission status at the time of transplant, and type of conditioning regimen. In the chronic GVHD category, “positive” means clinically extensive disease.