Correlation of Blood B Cells (CD19%) and Clonal B Cells (%PCR+) in PBL of Myeloma Patients
Patient ID . | Stage . | BM% PC* . | PBL% CD19+† . | PBL% PCR+‡ . |
---|---|---|---|---|
MM1 | 2A | 16 | 12 | 0.47 |
MM2 | 3A | 15 | 21 | <.0001 |
MM3 | 3A | 68 | 34 | 0.009 |
MM4 | 3B | 23 | 13 (12) | 3.6 (0.075) |
MM5 | 1A | 40 | 14 | 0.21 |
MM6 | 1A | 3 | 5 | 0.0014 |
MM7 | 2A | 3 | 6 (13) | 0.008 (.0001) |
MM8 | 3B | 38 | 13 (34) | 0.03 (.24) |
MM9 | 3A | 2 | 15 (20) | 1.6 (0.45) |
MM10 | 2B | 12 | 15 | 0.11 |
MM11 | 3A | 26 | 6 | 0.10 |
MM12 | 3A | 24 | 5 | 0.23 |
MM13 | 3B | 36 | 51 | 0.25 |
Patient ID . | Stage . | BM% PC* . | PBL% CD19+† . | PBL% PCR+‡ . |
---|---|---|---|---|
MM1 | 2A | 16 | 12 | 0.47 |
MM2 | 3A | 15 | 21 | <.0001 |
MM3 | 3A | 68 | 34 | 0.009 |
MM4 | 3B | 23 | 13 (12) | 3.6 (0.075) |
MM5 | 1A | 40 | 14 | 0.21 |
MM6 | 1A | 3 | 5 | 0.0014 |
MM7 | 2A | 3 | 6 (13) | 0.008 (.0001) |
MM8 | 3B | 38 | 13 (34) | 0.03 (.24) |
MM9 | 3A | 2 | 15 (20) | 1.6 (0.45) |
MM10 | 2B | 12 | 15 | 0.11 |
MM11 | 3A | 26 | 6 | 0.10 |
MM12 | 3A | 24 | 5 | 0.23 |
MM13 | 3B | 36 | 51 | 0.25 |
All data, with the exception of the peripheral blood lymphocytes (PBL)% CD19+, have been reported previously in Billadeau et al.11
Bone marrow (BM) percent (%) based on Southern blot analysis of marrow DNA probed with a J(H) probe.
PBL% CD19+ is the percent of CD19+ cells detected by flow cytometry and calculated as described in Materials and Methods.
All values are initial diagnosis samples, except numbers in parentheses, which represent samples analyzed after 2 months of therapy.